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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
31 Results for "
LNP systems
" in MedChemExpress (MCE) Product Catalog:
Products (31)
31 Results for "LNP systems" in MCE Product Catalog:
Cat. No.: HY-W040193S6
CAS No.: 326495-37-8
Synonyms: 1,2-Distearoyl-sn-glycero-3-PC-d13; 1,2-Distearoyl-sn-glycero-3-phosphorylcholine-d13
Cat. No.: HY-165427
CAS No.: 2758820-82-3
Lipid 11 (Compound Lipid 1) is a cationic lipid for nucleic acid delivery. Lipid 11 forms lipid nanoparticles (LNPs) through electrostatic binding with nucleic acids (such as ceDNA). Lipid 11 forms complexes with negatively charged nucleic acids via cationic amine groups, which can be endocytosed by cells to release nucleic acids for activity. Lipid 11 is promising for research of gene therapy drug delivery systems .
Cat. No.: HY-P11886
Synonyms: GNYTCEVTELTREGETIIELK-Azide
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Cat. No.: HY-W1130456
CAS No.: 2855180-86-6
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Lipid TD5 is an ionizable cationic lipid with a pKa value of 7.3. Lipid TD5 can be used to prepare lipid nanoparticles (LNPs), which efficiently deliver mRNA and the CRISPR/Cas9 system to the central nervous system and enable their expression .
Cat. No.: HY-182097
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DSPE-PEG1000-GNYTCEVTELTREGETIIELK is a PEG compound which composed of DSPE and a peptide mimicking the function of CD47 (GNYTCEVTELTREGETIIELK). Modifying the surface of LNPs with GNYTCEVTELTREGETIIELK significantly reduced the recognition and clearance of LNPs by the mononuclear phagocytic system (MPS), and decreased their accumulation in non-target tissues such as the liver and spleen. DSPE-PEG1000-GNYTCEVTELTREGETIIELK can be used for drug delivery .
Cat. No.: HY-182097A
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DSPE-PEG3400-GNYTCEVTELTREGETIIELK is a PEG compound which composed of DSPE and a peptide mimicking the function of CD47 (GNYTCEVTELTREGETIIELK). Modifying the surface of LNPs with GNYTCEVTELTREGETIIELK significantly reduced the recognition and clearance of LNPs by the mononuclear phagocytic system (MPS), and decreased their accumulation in non-target tissues such as the liver and spleen. DSPE-PEG3400-GNYTCEVTELTREGETIIELK can be used for drug delivery .
Cat. No.: HY-182097B
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DSPE-PEG5000-GNYTCEVTELTREGETIIELK is a PEG compound which composed of DSPE and a peptide mimicking the function of CD47 (GNYTCEVTELTREGETIIELK). Modifying the surface of LNPs with GNYTCEVTELTREGETIIELK significantly reduced the recognition and clearance of LNPs by the mononuclear phagocytic system (MPS), and decreased their accumulation in non-target tissues such as the liver and spleen. DSPE-PEG5000-GNYTCEVTELTREGETIIELK can be used for drug delivery .
Cat. No.: HY-184519
DSPE-PEG2000-Mal-Cys-SKIFNIHPOSTP is a PEG compound composed of DSPE and a cysteine-containing polypeptide (Cys-SKIFNIHPOSTP). DSPE-PEG2000-Mal-Cys-YEQDPWGVKWWY is commonly used to construct targeted liposomes, LNPs (lipid nanoparticles), micelles, or nanomedicine delivery systems.
Cat. No.: HY-K2035
MCE Fluc mRNA (N1-Me-pUTP) is widely used for evaluating lipid nanoparticle (LNP) delivery efficiency, validating mRNA transfection reagents, assessing in vitro and in vivo mRNA expression, IVIS bioluminescence imaging, and screening novel nucleic acid delivery systems. It is commonly used as a positive control or reporter mRNA.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
