DSPE-PEG2000-Mal-Cys-SKIFNIHPOSTP
DSPE-PEG2000-Mal-Cys-SKIFNIHPOSTP is a PEG compound composed of DSPE and a cysteine-containing polypeptide (Cys-SKIFNIHPOSTP). DSPE-PEG2000-Mal-Cys-YEQDPWGVKWWY is commonly used to construct targeted liposomes, LNPs (lipid nanoparticles), micelles, or nanomedicine delivery systems.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
生物活性
製品説明
体外実験
DSPE: Acts as a hydrophobic anchor, responsible for securely embedding the entire molecule into the membrane structure of the lipid nanoparticle.
PEG chain: Acts as a hydrophilic spacer arm, forming a hydration layer on the particle surface, reducing nonspecific adsorption and immune system recognition and clearance, and prolonging the carrier's circulation time in vivo.
Maleimide: A reaction interface located at the end of the PEG chain, capable of undergoing a specific Michael addition reaction with thiol-containing (-SH) biomolecules (such as peptides, antibodies, aptamers) to achieve targeting or tracking functions.
Cys-SKIFNIHPOSTP: The thiol group on Cys can react with Maleimide to form a stable thioether bond.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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SMILES
CCCCCCCCCCCCCCCCCC(O[C@@](COC(CCCCCCCCCCCCCCCCC)=O)([H])COP(OCCNC(OCCOCCNC(CC[Mal-Cys-SKIFNIHPOSTP])=O)=O)(O)=O)=O
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)