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Cat. No.: HY-184519

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DSPE-PEG2000-Mal-Cys-SKIFNIHPOSTP

DSPE-PEG2000-Mal-Cys-SKIFNIHPOSTP is a PEG compound composed of DSPE and a cysteine-containing polypeptide (Cys-SKIFNIHPOSTP). DSPE-PEG2000-Mal-Cys-YEQDPWGVKWWY is commonly used to construct targeted liposomes, LNPs (lipid nanoparticles), micelles, or nanomedicine delivery systems.

For research use only. We do not sell to patients.

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

DSPE-PEG2000-Mal-Cys-SKIFNIHPOSTP Chemical Structure

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vitro
Chemical Information
Purity & Documentation
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Bioz

Biological Activity

Description

In Vitro

DSPE: Acts as a hydrophobic anchor, responsible for securely embedding the entire molecule into the membrane structure of the lipid nanoparticle.
PEG chain: Acts as a hydrophilic spacer arm, forming a hydration layer on the particle surface, reducing nonspecific adsorption and immune system recognition and clearance, and prolonging the carrier's circulation time in vivo.
Maleimide: A reaction interface located at the end of the PEG chain, capable of undergoing a specific Michael addition reaction with thiol-containing (-SH) biomolecules (such as peptides, antibodies, aptamers) to achieve targeting or tracking functions.
Cys-SKIFNIHPOSTP: The thiol group on Cys can react with Maleimide to form a stable thioether bond.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

SMILES

CCCCCCCCCCCCCCCCCC(O[C@@](COC(CCCCCCCCCCCCCCCCC)=O)([H])COP(OCCNC(OCCOCCNC(CC[Mal-Cys-SKIFNIHPOSTP])=O)=O)(O)=O)=O
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.