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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
177 Results for "
MHC+Class+I
" in MedChemExpress (MCE) Product Catalog:
Products (177)
177 Results for "MHC+Class+I" in MCE Product Catalog:
Cat. No.: HY-P1837
CAS No.: 186302-15-8
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Cat. No.: HY-P10581A
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Cat. No.: HY-P10582A
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Cat. No.: HY-P990190
Cat. No.: HY-P990194
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Cat. No.: HY-P990192
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Cat. No.: HY-P990191
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Cat. No.: HY-P990813
Cat. No.: HY-152830A
Purity: 99.82%
Synonyms: Q702 TFA
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Adrixetinib (Q702) TFA is an orally active triple inhibitor against CSF1R, Mer, and Axl, with Kd values of 8.7 nM, 0.8 nM, and 0.3 nM, respectively. Adrixetinib TFA acts as a potent immune modulator that remodels the tumor microenvironment. Adrixetinib TFA increases the abundance of M1 macrophages and CD8⁺ T cells, while decreasing the levels of M2 macrophages and myeloid-derived suppressor cells (MDSCs). Adrixetinib TFA upregulates the expression of MHC class I and E-cadherin in tumor cells. Adrixetinib TFA shows remarkable antitumor efficacy in syngeneic mouse tumor models. Adrixetinib TFA is suitable for the research of breast cancer, renal adenocarcinoma, colon carcinoma, and melanoma .
Cat. No.: HY-P11061
CAS No.: 2036056-69-4
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Cat. No.: HY-P4044
CAS No.: 168417-72-9
Cat. No.: HY-P10296
CAS No.: 153147-67-2
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Cat. No.: HY-P991799
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Cat. No.: HY-P991806
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Cat. No.: HY-P991786
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Cat. No.: HY-P10245
CAS No.: 406477-46-1
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Cat. No.: HY-P991751
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Cat. No.: HY-P10840
CAS No.: 716361-65-8
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Cat. No.: HY-P990162
Synonyms: AB1-2
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Cat. No.: HY-P990244
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
