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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
43 Results for "
SAC
" in MedChemExpress (MCE) Product Catalog:
Products (43)
43 Results for "SAC" in MCE Product Catalog:
Cat. No.: HY-RS21204
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Tas1r3 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Tas1r3 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-N16371
CAS No.: 39051-96-2
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Cat. No.: HY-RS12411
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SACS Human Pre-designed siRNA Set A contains three designed siRNAs for SACS gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS00327
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ADCY10 Human Pre-designed siRNA Set A contains three designed siRNAs for ADCY10 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-161287
HDAC6-IN-32 (compound 25202) is a selective and potent inhibitor of HDAC6. HDAC6-IN-32 blocks HDAC6 activity and interferes with microtubule dynamics, leading to SAC activation and prolonged mitotic arrest, ultimately leading to apoptosis in CRPC cells .
Cat. No.: HY-N10597
CAS No.: 142473-98-1
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Cat. No.: HY-RS18004
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Adcy10 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Adcy10 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-E71103
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(R)-Mandelonitrile oxidase (EC 1.1.3.49) , characterized from the millipede Chamberlinius hualienensis, is segregated from its substrate, which is contained in special sacs. The sacs are ruptured during defensive behavior, allowing the enzyme and substrate to mix in special reaction chambers leading to production of the defensive chemical benzoyl cyanide.
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Cat. No.: HY-14644R
CAS No.: 541550-19-0
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Apilimod (Standard) is the analytical standard of Apilimod (HY-14644). This product is intended for research and analytical applications. Apilimod (STA 5326) is a potent IL-12/IL-23 inhibitor, and strongly inhibits IL-12 with IC50s of 1 nM and 2 nM, in IFN-γ/SAC-stimulated human PBMCs and SAC-treated monkey PBMCs, respectively . Apilimod is a potent and highly selective PIKfyve inhibitor.
Cat. No.: HY-W415799
CAS No.: 1658458-26-4
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(2S)-Ac4GalNAl can be used for the identification and characterization of specific surface groups of glycoproteins. The alkyne groups can react with azides via copper-catalyzed Click Chemistry. The acetyl groups on the glucose allow for easier penetration through the cell membrane.
Cat. No.: HY-P82771A
Synonyms: YVS; BTOP; SAC3; ALS11; CMT4J; KIAA0274; dJ249I4.1
Cat. No.: HY-103194R
CAS No.: 330676-02-3
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KH7 (Standard) is the analytical standard of KH7 (HY-103194). This product is intended for research and analytical applications. KH7 is a soluble adenylyl cyclase (sAC)-specific inhibitor, with IC50s of 3-10 μM toward both recombinant purified human sACt protein and heterologously expressed sACt in cellular assays . KH7 is also a cAMP inhibitor .
Cat. No.: HY-100341R
CAS No.: 312271-03-7
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M2I-1 (Standard) is the analytical standard of M2I-1 (HY-100341). This product is intended for research and analytical applications. M2I-1 is a Mad2 inhibitor targeting the binding of Mad2 to Cdc20, an essential protein-protein interaction (PPI) within the spindle assembly checkpoint (SAC) .
Cat. No.: HY-189231
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ARV-771-Azobenzene is an azide-containing PROTAC-Linker conjugate for the construction of PROTAC-antibody conjugates (PACs), consisting of the BRD4 PROTAC ARV-771 (HY-100972) and an azobenzene linker cleavable by azoreductase. ARV-771-Azobenzene acts as a payload for conjugation with DBCO-modified antibodies. Conjugation of ARV-771-Azobenzene with DBCO-modified Sacituzumab generates the azoreductase-cleavable SAC-ARV-771 conjugate (ASA). Conjugation of ARV-771-Azobenzene with DBCO-modified IgG generates IgG-ARV-771. ARV-771-Azobenzene is applicable to studies on hypoxia-responsive antibody-PROTAC conjugates and triple-negative breast cancer .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
