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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
25 Results for "
TC-PTP
" in MedChemExpress (MCE) Product Catalog:
Products (25)
25 Results for "TC-PTP" in MCE Product Catalog:
Cat. No.: HY-170582
Target:
Research Areas:
PTP1B-IN-29 (Compound A2B5) is an inhibitor for phosphatase, that inhibits protein tyrosine phosphatase 1B (PTP1B), TCPTP and λPPase with IC50s of 1.27 μM, 4.38 μM and 8.79 μM, respectively. PTP1B-IN-29 can be used in research of diabete and obesity .
Cat. No.: HY-174322
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Research Areas:
SHP2-IN-38 is a novel green-fluorescent SHP2 inhibitor with IC50 values of 2.89 μM (SHP2), 8.73 μM (SHP1), 11.08 μM (PTP1B), 33.07 μM (TCPTP). SHP2-IN-38 blocks the SHP2-mediated ERK signaling pathway and inhibits MV4-11 cells proliferation in vitro with IC50 of 7.90 μM. SHP2-IN-38 has an excitation wavelength of 360 nm, with a maximum emission wavelength of 550 nm in DMSO and 540 nm in DMF. SHP2-IN-38 shows green fluorescence imaging in HeLa cells and zebrafish.
Cat. No.: HY-P87102
Synonyms: Protein tyrosine phosphatase non receptor type 2 antibody; PTN2 antibody; PTN2_HUMAN antibody; PTPN 2 antibody; PTPn2 antibody; PTPT antibody; T cell protein tyrosine phosphatase antibody; T-cell protein-tyrosine phosphatase antibody; TC PTP antibody; TCELLPTP antibody; Protein tyrosine phosphatase non receptor type 2 antibody; PTN2 antibody; PTN2_HUMAN antibody; PTPN 2 antibody; PTPn2 antibody; PTPT antibody; T cell protein tyrosine phosphatase antibody; T-cell protein-tyrosine phosphatase antibody; TC PTP antibody; TCELLPTP antibody; TCPTP antibody; Tyrosine protein phosphatase non receptor type 2 antibody; Tyrosine-protein phosphatase non-receptor type 2 antibody;
Cat. No.: HY-189266
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Research Areas:
PTP1B-IN-36 is a PTP1B inhibitor (IC50 0.70 μM) and a SHP2-E76K inhibitor (IC50 0.36 μM). PTP1B-IN-36 exhibits broad-spectrum inhibitory activity against PTP family enzymes, including TCPTP, SHP1-PTP, SHP2-PTP, and SHP1-WT. PTP1B-IN-36 shows anticancer activity against osteosarcoma. PTP1B-IN-36 can be used for research on osteosarcoma .
Cat. No.: HY-183801
Target:
Research Areas:
Cu2LCl2(H2O) acts as a proteasome inhibitor and protein tyrosine phosphatase inhibitor, with antiproliferative and apoptosis-inducing effects. Cu2LCl2(H2O) exhibits low cytotoxicity against normal cells and remarkable in vivo antitumor efficacy. Cu2LCl2(H2O) inhibits proteasome activity in colon cancer cells, and suppresses PTP1B and TCPTP activities in breast cancer cells. Cu2LCl2(H2O) can be used in the research of colon cancer, breast cancer and liver cancer .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
