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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
31 Results for "
monkey plasma
" in MedChemExpress (MCE) Product Catalog:
Products (31)
31 Results for "monkey plasma" in MCE Product Catalog:
Cat. No.: HY-117637
CAS No.: 1369357-99-2
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ALS-I-41 is a novel, potent and selective oxytocin receptor antagonist with the potential to modulate biological activities related to social behavior and mental disorders. ALS-I-41 is being evaluated for behavioral pharmacology experiments in non-human primates and can be administered via intranasal or intramuscular injection. The central nervous system penetration and metabolic rate of ALS-I-41 were studied by mass spectrometry analysis in cerebrospinal fluid and plasma of macaque monkeys .
Cat. No.: HY-B0890A
CAS No.: 33369-31-2
Synonyms: McN-2783-21-98 free acid
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Zomepirac (McN-2783-21-98 free acid) is an orally active prostaglandin synthetase inhibitor. Zomepirac blocks prostaglandin synthesis and inhibits Collagen (HY-P72147)- or Epinephrine (HY-B0447)-induced platelet aggregation. Zomepirac can be used for the research of postoperative pain and osteoarthritis .
Cat. No.: HY-B0890R
CAS No.: 64092-48-4
Synonyms: McN-2783-21-98 (Standard)
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Zomepirac sodium salt (Standard) is the analytical standard of Zomepirac sodium salt (HY-B0890). This product is intended for research and analytical applications. Zomepirac sodium salt (McN-2783-21-98) is an orally active prostaglandin synthetase inhibitor. Zomepirac sodium salt blocks prostaglandin synthesis and inhibits Collagen (HY-P72147)- or Epinephrine (HY-B0447)-induced platelet aggregation. Zomepirac sodium salt can be used for the research of postoperative pain and osteoarthritis .
Cat. No.: HY-119036
CAS No.: 105186-68-3
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KRI-1177 is a competitive, dipeptide human renin inhibitor with a Ki of 0.7 μM and an IC50 of 90 nM. The IC50 of KRI-1177 targeting cynomolgus monkey renin is 680 nM. KRI-1177 acts as an antihypertensive agent, angiotensin inhibitor and plasma renin activity inhibitor, which reduces systemic blood pressure and plasma angiotensin concentration. KRI-1177 exhibits a relatively long-lasting antihypertensive effect in cynomolgus monkeys and can be used for hypertension research .
Cat. No.: HY-129737
CAS No.: 117978-26-4
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A-62198 is a potent and selective renin inhibitor with antihypertensive activity. A-62198 reduces mean arterial pressure (MAP) in anesthetized, salt-deprived monkeys in a dose-dependent manner. A-62198 induced MAP reduction in normal monkeys that reached statistical significance at the highest dose and significantly inhibited plasma renin activity (PRA) at all doses .
Cat. No.: HY-P992313
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Cat. No.: HY-115499A
CAS No.: 1310540-31-8
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MPC-0767 free base is an orally active prodrug of Hsp90 inhibitor. MPC-0767 free base undergoes rapid biotransformation to the parent Hsp90 inhibitor MPC-3100 via enzyme-mediated luminal cleavage. MPC-0767 free base is applicable to the research of refractory and recurrent cancers .
Cat. No.: HY-183978
CAS No.: 128053-53-2
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KRI-1314 is an orally active human renin inhibitor with selectivity for primate renin over non-primate renin. KRI-1314 competitively inhibits the binding of recombinant human renin to its substrate, reduces plasma renin activity, lowers blood pressure, and exhibits high stability in tissue homogenates. KRI-1314 is applicable to research on renin-dependent hypertension and hypertension-related studies .
Cat. No.: HY-183983
CAS No.: 2173066-25-4
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PAR4 antagonist 9 is an orally active protease-activated receptor 4 (PAR4) antagonist with an IC50 of 2 nM against human targets. PAR4 antagonist 9 functionally modulates PAR4 and inhibits platelet aggregation. PAR4 antagonist 9 can be used in studies related to arterial thrombosis .
Cat. No.: HY-185492
CAS No.: 1799659-90-7
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MC-cBu-Cit-seco-CBI dimer (Compound 10) is a conjugate of an ADC drug toxin molecule and a linker, which consists of a DNA alkylating agent connected to a reactive maleimide via a protease-cleavable peptidomimetic linker .
Cat. No.: HY-P11771
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KS-487 is a cyclic peptide targeting LRP1 that binds to cluster IV (CL4) domain of LRP1 and facilitates molecular delivery to brain tissue via receptor-mediated transcytosis (RMT). The EC50 of KS-487 binding to human LRP1 (CL4) is 10.5 nM. Compared with Angiopep-2, KS-487 exhibits enhanced brain selectivity and can be used in studies related to brain-targeted delivery systems .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
