A-62198
A-62198 is a potent and selective renin inhibitor with antihypertensive activity. A-62198 reduces mean arterial pressure (MAP) in anesthetized, salt-deprived monkeys in a dose-dependent manner. A-62198 induced MAP reduction in normal monkeys that reached statistical significance at the highest dose and significantly inhibited plasma renin activity (PRA) at all doses.
For research use only. We do not sell to patients.
- CAS No.: 117978-26-4
- Formula: C30H44N8O5
- Molecular Weight:596.72
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
Chemical Information
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CAS No. 117978-26-4
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Molecular Weight 596.72
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Formula C30H44N8O5
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SMILES
O[C@@H]([C@H](CN=[N+]=[N-])O)[C@@H](NC([C@H](CC1=CNC=N1)NC([C@H](CC2=CC=CC=C2)NC(C(C)C)=O)=O)=O)CC3CCCCC3
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
A-62198 Related Classifications
HY-129737 Related Classifications
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