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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
128 Results for "
pgf2
" in MedChemExpress (MCE) Product Catalog:
Products (128)
128 Results for "pgf2" in MCE Product Catalog:
Cat. No.: HY-116051A
CAS No.: 59769-89-0
Synonyms: 16,16-Dimethyl-pgf2β
Target:
Research Areas:
16,16-Dimethylprostaglandin F2β (16,16-Dimethyl-PGF2β) is an analog of PGF2β (HY-12956B), which is an irratant, but prevents the aspecifically induced bronchospasm .
Cat. No.: HY-137504
CAS No.: 36950-85-3
Synonyms: ICI 74205; 20-ethyl pgf2α
Research Areas:
20-ethyl Prostaglandin F2α (ICI 74205; 20-ethyl PGF2α) is an analog of PGF2α and an arachidonic acid (HY-109590) metabolite.
Cat. No.: HY-W399193
CAS No.: 55314-48-2
Synonyms: Prostaglandin F2α 1,9-lactone
Target:
Research Areas:
PGF2α 1,9-lactone (Prostaglandin F2α 1,9-lactone) is a prostaglandin lactone. PGF2α 1,9-lactone shows resistant to hydrolysis by plasma esterases .
Cat. No.: HY-116679
CAS No.: 221246-34-0
Synonyms: 17-Trifluoromethylphenyl trinor pgf2α
Target:
Research Areas:
A number of 17-phenyl trinor prostaglandin F2α (17-phenyl trinor PGF2α) derivatives have been approved for glaucoma. Of these, the unsubstituted or meta-substituted aromatic derivatives are the most potent FP receptor agonists.4 17-trifluoromethylphenyl trinor PGF2α bears an aromatic ring which is reminiscent of the trifluoromethyl-phenoxy ring of travoprost ((+)-fluprostenol isopropyl ester). As an ocular hypotensive agent, it would be expected that 17-trifluoromethylphenyl trinor PGF2α would act very much like the free acid of travoprost. 17-phenyl trinor PGF2α is a potent luteolytic, with a potency equal to or greater than fluprostenol and cloprostenol.
Cat. No.: HY-128550
CAS No.: 35700-21-1
Synonyms: Methyl carboprost; 15(S)-15-Methyl pgf2α methyl ester; U-36384
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Research Areas:
15(S)-15-methyl Prostaglandin F2α methyl ester (15(S)-15-methyl PGF2α methyl ester) is a derivative of 15(S)-15-methyl PGF2α with increased membrane permeability. Hydrolysis of the methyl ester in vivo releases the biologically active 15(S)-15-methyl PGF2α, which is a potent uterine stimulant and abortifacient.
Cat. No.: HY-158571
CAS No.: 2162157-41-5
Synonyms: 17-Phenoxy trinor pgf2α
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Research Areas:
17-Phenoxy trinor prostaglandin F2α is a PGF2α analog .
Cat. No.: HY-138244
CAS No.: 177020-26-7
Synonyms: 8-iso pgf2β
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Research Areas:
8-iso Prostaglandin F2β (8-iso PGF2β) is a biomarker for assessing oxidative stress, and its content in serum can indirectly reflect the level of oxidative stress .
Cat. No.: HY-N7857
CAS No.: 64625-53-2
Synonyms: 19(R)-Hydroxy pgf2α
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Target:
Cat. No.: HY-158595
CAS No.: 1224444-23-8
Synonyms: 15(R),19(R)-Hydroxy pgf2α
Target:
Research Areas:
15(R),19(R)-Hydroxy prostaglandin F2α (15(R),19(R)-Hydroxy PGF2α) is an analog of 19(R)-Hydroxy-prostaglandin F2α. 19(R)-Hydroxy-prostaglandin F2α (HY-N7857) is an ω-1 hydroxylase metabolite of PGF2α found in human semen .
Cat. No.: HY-113246
CAS No.: 35850-13-6
Synonyms: 15-keto-pgf2α
Cat. No.: HY-113208A
CAS No.: 107615-77-0
Synonyms: 11β-13,14-Dihydro-15-keto pgf2α; 11-epi-13,14-dihydro-15-keto pgf2α
Target:
Research Areas:
11β-13,14-Dihydro-15-keto Prostaglandin F2α is the deviative of 13,14-Dihydro-15-keto PGF2a (HY-113208), which is an endogenous metabolite present in Blood that can be used for the research of Pregnancy [2].
Cat. No.: HY-131632
CAS No.: 57944-39-5
Synonyms: 1a,1b-Dihomo-pgf2α
Target:
Research Areas:
1a,1b-Dihomo prostaglandin F2α (1a,1b-Dihomo-PGF2α) is the derivative of Prostaglandin F2α (HY-12956) .
Cat. No.: HY-139124
CAS No.: 35864-81-4
Synonyms: 15(R)-Carboprost; 15(R)-15-methyl pgf2α
Target:
Research Areas:
15(R)-15-Methyl Prostaglandin F2α (15(R)-Carboprost; 15(R)-15-methyl PGF2α) is a metabolically stable analog of PGF2α. 15(R)-15-Methyl Prostaglandin F2α is an inactive, prodrug PGF agonist designed for activation by gastric acid after oral administration. Acid-catalyzed epimerization of 15(R)-15-Methyl Prostaglandin F2α converts it into the active 15(S)-isomer. The 15(S)-isomer induces luteolysis when injected in rhesus monkeys at a dose of about 12 mg/animal, while the 15(R)-isomer does not.
Cat. No.: HY-118294
CAS No.: 130209-78-8
Synonyms: 16-Phenoxy tetranor prostaglandin F2α isopropyl ester; 16-Phenoxy tetranor pgf2α isopropyl ester
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Research Areas:
15-OH Tafluprost, a prostaglandin F2a (PGF2a) analog, relieves endothelin-1 (ET-1)-induced optic nerve head (ONH) blood flow impairment and ET-1-induced contraction of isolated ciliary artery segments .
Cat. No.: HY-129397
CAS No.: 240405-20-3
Synonyms: BPG; 2,3-Dinor-11β-pgf2α; 2,3-dinor-11-epi pgf2α
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Research Areas:
2,3-Dinor-11beta-prostaglandin F2alpha (2,3-Dinor-11β-PGF2α) is a metabolite of PGD2. Urinary excretion of 2,3-Dinor-11beta-prostaglandin F2alpha is increased in patients with mast cell activation disease (MCAD) and has been used as a marker of increased PGD2 levels. 2,3-Dinor-11beta-prostaglandin F2alpha levels are also increased in the urine of patients with asthma and are positively correlated with impaired lung function.
Cat. No.: HY-125626
CAS No.: 191919-01-4
Synonyms: 8-iso-15-keto pgf2α
Target:
Research Areas:
8-iso-15-keto Prostaglandin F2α (8-iso-15-keto PGF2α) is a partial agonist for Thromboxane receptor (TP), which exhibits a vasoconstrictor efficacy with a pD2 of 5.8. 8-iso-15-keto Prostaglandin F2α mediates a weak relaxation of rats aorta rings at high concentration .
Cat. No.: HY-124219
CAS No.: 1421369-12-1
Synonyms: 17-Phenoxy trinor pgf2α ethyl amide
Target:
Research Areas:
17-Phenoxy trinor prostaglandin F2α ethyl amide (17-Phenoxy trinor PGF2α ethyl amide) is an analog of Bimatoprost (HY-12956). 17-Phenoxy trinor prostaglandin F2α ethyl amide is an agonist for Prostaglandin F2α Receptor (FP receptor). 17-Phenoxy trinor prostaglandin F2α ethyl amide is potent to reduce the intraocular pressure and attenuate the glaucoma [2].
Cat. No.: HY-176096
Synonyms: 1α-Monohomo-17-phenyl trinor pgf2α
Target:
Research Areas:
1α-Monohomo-17-phenyl trinor Prostaglandin F2α (1α-Monohomo-17-phenyl trinor PGF2α) is a derivative of 17-phenyl trinor prostaglandin F2α ethyl amide. 1α-Monohomo-17-phenyl trinor Prostaglandin F2α is also an isomer of 17-phenyl trinor prostaglandin F2α methyl ester.
Cat. No.: HY-113778
CAS No.: 949564-89-0
Synonyms: 15-keto-17-phenyl trinor pgf2α
Target:
Research Areas:
15-keto-17-phenyl trinor Prostaglandin F2α (15-keto-17-phenyl trinor PGF2α) is an F-series prostaglandin (PG) analog. The potential metabolite of 15-keto-17-phenyl trinor Prostaglandin F2α in animals is 15-keto PG. 15-keto PG can slightly reduce the intraocular pressure (1 mm Hg) in normal cynomolgus monkeys when administered at a dose of 1 μg/eye. 15-keto-17-phenyl trinor Prostaglandin F2α is a miotic agent in cats, reducing the pupil diameter by 8 mm at a dose of 5 μg/eye.
Cat. No.: HY-113459S1
CAS No.: 42932-59-2
Synonyms: 13,14-Dihydro-15-keto-pgf2α-d4
Research Areas:
13,14-Dihydro-15-keto Prostaglandin F2α-d4 (13,14-Dihydro-15-keto-PGF2α-d4) is a deuterated labeled 13,14-Dihydro-15-keto Prostaglandin F2α (HY-113208). 13,14-Dihydro-15-keto Prostaglandin F2α-d4 is an endogenous metabolite present in Blood that can be used for the research of Pregnancy [2].
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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
