130209-78-8
Chemical Structure
15-OH Tafluprost
Synonym(s): 16-Phenoxy tetranor prostaglandin F2α isopropyl ester; 16-Phenoxy tetranor PGF2α isopropyl ester
- CAS No.: 130209-78-8
- Formula:C25H36O6
- Molecular Weight:432.55
IUPAC Name: isopropyl (Z)-7-((1R,2R,3R,5S)-3,5-dihydroxy-2-((R,E)-3-hydroxy-4-phenoxybut-1-en-1-yl)cyclopentyl)hept-5-enoate
InChIKey: DRPNUICIWHCOON-HQUSFCFYSA-N
SMILES: CC(C)OC(CCC/C=C\C[C@@H]1[C@H]([C@@H](C[C@@H]1O)O)/C=C/[C@@H](O)COC2=CC=CC=C2)=O
Biological Activity: 15-OH Tafluprost, a prostaglandin F2a (PGF2a) analog, relieves endothelin-1 (ET-1)-induced optic nerve head (ONH) blood flow impairment and ET-1-induced contraction of isolated ciliary artery segments[1].
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15-OH Tafluprost | 15-OH Tafluprost, a prostaglandin F2a (PGF2a) analog, relieves endothelin-1 (ET-1)-induced optic nerve head (ONH) blood flow impairment and ET-1-induced contraction of isolated ciliary artery segments. | |||||||||||||||||||||
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