35850-13-6

15-keto-Prostaglandin F2a Chemical Structure
35850-13-6

Chemical Structure

15-keto-Prostaglandin F2a

Synonym(s): 15-keto-PGF2α

  • CAS No.: 35850-13-6
  • Formula:C20H32O5
  • Molecular Weight:352.47

IUPAC Name: (Z)-7-((1R,2R,3R,5S)-3,5-dihydroxy-2-((E)-3-oxooct-1-en-1-yl)cyclopentyl)hept-5-enoic acid

InChIKey: LOLJEILMPWPILA-AMFHKTBMSA-N

SMILES: CCCCCC(/C=C/[C@@H]1[C@H]([C@@H](O)C[C@H]1O)C/C=C\CCCC(O)=O)=O

Biological Activity: 15-keto-Prostaglandin F2a (15-keto-PGF2α) is a key oxidative metabolite of the primary prostaglandin PGF2α in vivo. The prostaglandin receptor agonist activity of 15-keto-Prostaglandin F2a itself is significantly attenuated. 15-keto-Prostaglandin F2a acts as a pro-inflammatory lipid mediator that potently binds to OPG, RANKL and TRAF6, and its level is significantly elevated in the serum of collagen-induced arthritis mice. 15-keto-Prostaglandin F2a can be used for the study of rheumatoid arthritis[1].
The product specifications provided below refer solely to the active content of 15-keto-Prostaglandin F2a.

Cat. No. Product Name Purity Description Pricing
HY-113246
15-keto-Prostaglandin F2a 99.2% 15-keto-Prostaglandin F2a (15-keto-PGF2α) is a key oxidative metabolite of the primary prostaglandin PGF2α in vivo. The prostaglandin receptor agonist activity of 15-keto-Prostaglandin F2a itself is significantly attenuated. 15-keto-Prostaglandin F2a acts as a pro-inflammatory lipid mediator that potently binds to OPG, RANKL and TRAF6, and its level is significantly elevated in the serum of collagen-induced arthritis mice. 15-keto-Prostaglandin F2a can be used for the study of rheumatoid arthritis.
The product specifications provided below refer solely to the active content of 15-keto-Prostaglandin F2a.
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This compound is listed in the SVHC (Substances of Very High Concern) candidate list of ECHA (European Chemicals Agency).

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Structural Analogs

References