1421369-12-1
Chemical Structure
17-Phenoxy trinor prostaglandin F2α ethyl amide
Synonym(s): 17-Phenoxy trinor PGF2α ethyl amide
- CAS. Nr.: 1421369-12-1
- Formula:C25H37NO5
- Molecular Weight:431.56
IUPAC Name: (Z)-7-((1R,2R,3R,5S)-3,5-dihydroxy-2-((S,E)-3-hydroxy-5-phenoxypent-1-en-1-yl)cyclopentyl)-N-ethylhept-5-enamide
InChIKey: QGDXYIFHBPXXOY-HQUSFCFYSA-N
SMILES: O[C@@H]1[C@@H]([C@H]([C@@H](C1)O)/C=C/[C@H](CCOC2=CC=CC=C2)O)C/C=C\CCCC(N(CC)[H])=O
Biological Activity: 17-Phenoxy trinor prostaglandin F2α ethyl amide (17-Phenoxy trinor PGF2α ethyl amide) is an analog of Bimatoprost (HY-12956). 17-Phenoxy trinor prostaglandin F2α ethyl amide is an agonist for Prostaglandin F2α Receptor (FP receptor). 17-Phenoxy trinor prostaglandin F2α ethyl amide is potent to reduce the intraocular pressure and attenuate the glaucoma[1][2].
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17-Phenoxy trinor prostaglandin F2α ethyl amide | 17-Phenoxy trinor prostaglandin F2α ethyl amide (17-Phenoxy trinor PGF2α ethyl amide) is an analog of Bimatoprost (HY-12956). 17-Phenoxy trinor prostaglandin F2α ethyl amide is an agonist for Prostaglandin F2α Receptor (FP receptor). 17-Phenoxy trinor prostaglandin F2α ethyl amide is potent to reduce the intraocular pressure and attenuate the glaucoma. | |||||||||||||||||||||
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- [1]. Balapure AK, et al., Structural requirements for prostaglandin analog interaction with the ovine corpus luteum prostaglandin F2 alpha receptor. Implications for development of a photoaffinity probe. Biochem Pharmacol. 1989 Jul 15;38(14):2375-81. [Content Brief]
- [2]. Woodward DF, et al., Pharmacological characterization of a novel antiglaucoma agent, Bimatoprost (AGN 192024). J Pharmacol Exp Ther. 2003 May;305(2):772-85. [Content Brief]
