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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
169 Results for "
Pyrazole
" in MedChemExpress (MCE) Product Catalog:
Products (169)
169 Results for "Pyrazole" in MCE Product Catalog:
Cat. No.: HY-127133
CAS No.: 289726-02-9
Synonyms: MPP
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Methylpiperidino pyrazole (MPP) is a potent and selective ER (estrogen receptor) modulator. Methylpiperidino pyrazole induces significant apoptosis in the endometrial cancer and oLE cell lines. Methylpiperidino pyrazole reverses the the positive effects of beta-estradiol. Methylpiperidino pyrazole has mixed agonist/antagonist action on murine uterine ERalpha in vivo .
Cat. No.: HY-W779244
CAS No.: 51038-79-0
Cat. No.: HY-22365
CAS No.: 50920-65-5
Cat. No.: HY-W112721
CAS No.: 25240-33-9
Synonyms: 4-(1H-Pyrazol-4-yl)-1H-Pyrazole
1H,1'H-4,4'-Bipyrazole (4-(1H-Pyrazol-4-yl)-1H-pyrazole) is a metal-organic framework (MOF).
Cat. No.: HY-W075124
CAS No.: 958101-27-4
Synonyms: 4,4'-(1,3-Phenylene)bis-1H-Pyrazole
1,3-Di(1H-pyrazol-4-yl)benzene (4,4'-(1,3-Phenylene)bis-1H-pyrazole) is a metal-organic framework (MOF).
Cat. No.: HY-107448
CAS No.: 1026682-51-8
Synonyms: Protac cdk9-binding moiety 1
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1H-Pyrazole-1-carboxylic acid, 3-amino-5-cyclobutyl-, 1,1-dimethylethyl ester (Protac cdk9-binding moiety 1) is a drug intermediate for synthesis of various active compounds.
Synonyms: KVD-824
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Feniralstat (compound 30), a pyrazole derivative, is a potent kallikrein inhibitor with an IC50 of 6.7 nM for Human plasma kallikrein (pKal). Feniralstat has no inhibition on Human KLKl, Human FXIa, Human Factor Xlla (all IC50>40 μM) .
Cat. No.: HY-174170
CAS No.: 2248444-14-4
(S)-2-(1-Ethyl-3-methyl-1H-pyrazole-5-carboxamido)-1-(2-hydroxy-2-phenylethyl)-1H-benzo[d]imidazole-5-carboxamide (compound 4) is a STING agonist containing a key amide benzimidazole (ABZI) component and shows reproducible inhibition of 3H-cGAMP binding to STING with an apparent inhibition constant IC50 of 14 μM. (S)-2-(1-Ethyl-3-methyl-1H-pyrazole-5-carboxamido)-1-(2-hydroxy-2-phenylethyl)-1H-benzo[d]imidazole-5-carboxamide can be used for tumor research .
Cat. No.: HY-B1850
CAS No.: 100784-20-1
Synonyms: Inpool; MON 12000; Manage
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Halosulfuron-methyl is a pyrazole sulfonylurea herbicide .
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Cat. No.: HY-139994
CAS No.: 2820169-36-4
Synonyms: XP
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XN methyl pyrazole (XP) is an orally active, blood-brain barrier permeable uncoupler/proton carrier. XN methyl pyrazole uncouples oxidative phosphorylation, depolarizes mitochondrial transmembrane potential, increases energy expenditure, spontaneous activity levels, and cortical inosine monophosphate levels. XN methyl pyrazole reduces plasma purine and energy metabolite levels, improves glucose tolerance, and decreases weight gain, while avoiding potential estrogenic side effects. XN methyl pyrazole can be used in studies related to diet-induced obesity and insulin resistance .
Cat. No.: HY-100689R
CAS No.: 263717-53-9
Synonyms: PPT (Standard)
Research Areas:
Propyl pyrazole triol (Standard) is the analytical standard of Propyl pyrazole triol. This product is intended for research and analytical applications. Propyl pyrazole triol (PPT) is a selective estrogen receptor alpha (ERα) agonist. The relative binding affinity of Propyl pyrazole triol for ERα (ERα: 49%) around 410 times higher compared with estrogen receptor beta (ERβ: 0.12%) .
Cat. No.: HY-172297
CAS No.: 139755-95-6
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Pyrazole N-Desmethyl sildenafil (Compound 10) is an analog of Sildenafil (HY-15025). Pyrazole N-Desmethyl sildenafil shows 16% inhibition on Trypanosoma brucei phosphodiesterase B1 (TbrPDEB1) with 100 µM .
Cat. No.: HY-W017032R
CAS No.: 4023-02-3
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1-Ethyl-1H-pyrazole is a drug impurity.
Cat. No.: HY-Z1093
CAS No.: 32500-67-7
Synonyms: 1-PropylPyrazole
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1-Propyl-1H-pyrazole is a drug impurity.
Cat. No.: HY-168227
CAS No.: 2933254-71-6
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trans-Boronic acid pinacol-pyrazole-C-cyclobutane-O-piperidine-Boc is a PROTAC linker. trans-Boronic acid pinacol-pyrazole-C-cyclobutane-O-piperidine-Boc can be used in the synthesis of PROTAC SMARCA2/4-degrader-35 (HY-168225) .
Cat. No.: HY-W077074S
CAS No.: 2735654-39-2
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
