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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
107 Results for "
complement inhibitors
" in MedChemExpress (MCE) Product Catalog:
Products (107)
107 Results for "complement inhibitors" in MCE Product Catalog:
Cat. No.: HY-P3502A
Synonyms: RA101495 TFA; RA3193 TFA
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Cat. No.: HY-153098
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ARC186 (sodium) is an unconjugated 40KDa PEG aptamer with a sequence identical to HY-147080 Avacincaptad pegol (ARC1905) sodium. ARC1905 is highly potent complement inhibitors that function by blocking the convertase-catalyzed activation of C5.
Cat. No.: HY-P3204A
Synonyms: AL-78898A TFA
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Cat. No.: HY-P99886
CAS No.: 219685-93-5
Synonyms: h5G1. 1-SC
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Cat. No.: HY-P10274
CAS No.: 3037805-45-8
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Cat. No.: HY-W049802
CAS No.: 918531-01-8
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Cat. No.: HY-174913
CAS No.: 1644670-23-4
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Factor B-IN-5 is an orally active complement factor B (CFB) inhibitor. Factor B-IN-5 alleviates kidney damage in diabetes nephropathy by inhibiting the over activation of complement system and improving mitochondrial function. Factor B-IN-5 can improve renal tubulointerstitial inflammation and fibrosis. Factor B-IN-5 can be used for research on diabetic nephropathy .
Cat. No.: HY-178284
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Factor B-IN-7 (Compound (I)) is a selective Factor B inhibitor. Factor B-IN-7 inhibits Factor B-C3b interaction to suppress complement hyperactivation. Factor B-IN-7 is promising for research of paroxysmal nocturnal hemoglobinuria (PNH), C3 glomerulopathy, and age-related macular degeneration (AMD) associated with complement-mediated diseases .
Cat. No.: HY-P1398A
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Cat. No.: HY-W587516
CAS No.: 10040-44-5
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Bisphenol A bissulfate disodium is a metabolite of Bisphenol A (HY-18260) . Bisphenol A bissulfate disodium (compound 7) show complement-inhibiting activity with an IC50 of 247 μM .
Cat. No.: HY-E70390
Synonyms: masp-2, c1 esterase, c1-esterase
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C1s Enzyme is a subunit of the complement C1 complex, which activates the complement as a serine protease. C1s Enzyme cleaves LRP5 and LRP6, and thus activates the Wnt/β-Catenin signaling pathway. C1s Enzyme promotes the macrophage M2 polarization and inhibits M1 polarization. C1s Enzyme enhances efferocytosis, exhibits anti-inflammatory activity .
Cat. No.: HY-147605
CAS No.: 2760669-74-5
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Factor B-IN-3 (Example 3 target compound) is a potent complement factor B inhibitor. Factor B-IN-3 can be used for the research of diseases related to inflammation and immunity .
Cat. No.: HY-147606
CAS No.: 2760669-84-7
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Factor B-IN-4 (Example 13 target compound) is a potent complement factor B inhibitor, with an IC50 of 1 μM. Factor B-IN-4 can be used for the research of diseases related to inflammation and immunity .
Cat. No.: HY-147607
CAS No.: 2797066-85-2
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Factor B-IN-5 (Example 5 target compound) is a potent complement factor B inhibitor, with an IC50 of 1.2 μM. Factor B-IN-5 can be used for the research of diseases related to inflammation and immunity .
Cat. No.: HY-153098A
Purity: 94.13%
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ARC186 (sodium) is an unconjugated 40KDa PEG aptamer with a sequence identical to HY-147080 Avacincaptad pegol (ARC1905) sodium. ARC1905 is highly potent complement inhibitors that function by blocking the convertase-catalyzed activation of C5.
Cat. No.: HY-147604
CAS No.: 2760669-72-3
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Factor B-IN-2 (Example 1 target compound) is a potent complement factor B inhibitor, with an IC50 of 1.5 μM. Factor B-IN-2 can be used for the research of diseases related to inflammation and immunity .
Cat. No.: HY-153785
Purity: 92.50%
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NH2-C6-ARC186 sodium is a modified ARC186 (HY-153098) with NH2-C6 that can be coupled to other peptides or molecules. ARC186 is a aptamer and a highly potent complement inhibitor that function by blocking the convertase-catalyzed activation of C5 .
Cat. No.: HY-P991585
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Cat. No.: HY-P990753
CAS No.: 2763342-87-4
Synonyms: CAN-106
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Cat. No.: HY-P5509
CAS No.: 230968-98-6
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
