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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
84 Results for "
DDB
" in MedChemExpress (MCE) Product Catalog:
Products (84)
84 Results for "DDB" in MCE Product Catalog:
Cat. No.: HY-P87409A
Synonyms: DCAF3, KIAA1736, AMBRA1, Activating molecule in BECN1-regulated autophagy protein 1, DDB1- and CUL4-associated factor 3
Cat. No.: HY-181405
CAS No.: 2387704-74-5
Target:
Research Areas:
SR-5037 is an orally active CDK12 (IC50 = 31 nM)/CDK13 inhibitor and CycK (DC50 = 30 nM; Dmax > 98%) molecular glue degrader. SR-5037 inhibits the enzymatic activity of CDK12/CycK and CDK13/CycK complexes. SR-5037 promotes the recruitment of DDB1 to the CDK12/CycK complex, thereby triggering proteasome-mediated CycK degradation. SR-5037 degrades active CycK in mouse models of triple-negative breast cancer. SR-5037 can be used in the research of cancers such as triple-negative breast cancer .
Cat. No.: HY-P76833
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CLEC4A; C-Type Lectin Superfamily Member 6; Prev. CLECSF6; Lectin-Like Immunoreceptor; DCIR; C-Type Lectin DDB27; DDB27; LLIR; CD367; C-Type Lectin Domain Family 4, Member A; HDCIR; CD367 Antigen; C-Type (Calcium Dependent, Carbohydrate-Recognition Domain) Lectin, Superfamily Member 6; HDCGC13P; C-Type Lectin Domain Family 4 Member A; Dendritic Cell Immunoreceptor
Species:
Human
Source:
HEK293
Cat. No.: HY-P87301
Synonyms: AN11 antibody; Dcaf7 antibody; DCAF7_HUMAN antibody; DDB1- and CUL4-associated factor 7 antibody; HAN11 antibody; Human anthocyanin antibody; Petunia antibody; Seven WD repeat protein of the AN11 family 1 antibody; SWAN 1 antibody; WD repeat domain 68 antibody
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
