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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
117 Results for "
TOS
" in MedChemExpress (MCE) Product Catalog:
Products (117)
117 Results for "TOS" in MCE Product Catalog:
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Tos-PEG4-THP is a PEG-based PROTAC linker can be used in the synthesis of PROTAC K-Ras Degrader-1 (HY-129523) .
Cat. No.: HY-130158
CAS No.: 1643957-24-7
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Tos-PEG1-CH2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
Cat. No.: HY-130415
CAS No.: 1807537-35-4
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Tos-PEG2-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
Cat. No.: HY-130473
CAS No.: 2028284-73-1
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Tos-PEG4-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
Cat. No.: HY-130526
CAS No.: 1530777-90-2
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Tos-PEG6-CH2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
Cat. No.: HY-130674
CAS No.: 1581248-63-6
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Tos-PEG3-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
Cat. No.: HY-133071
CAS No.: 406213-75-0
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Tos-PEG6-C2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
Cat. No.: HY-140366
CAS No.: 1949793-62-7
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Tos-PEG5-CH2COOtBu is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
Cat. No.: HY-42620
CAS No.: 169751-73-9
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Tos-PEG4-CH2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
Cat. No.: HY-140375
CAS No.: 1239588-09-0
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Tos-PEG3-C2-methyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
Cat. No.: HY-125844
CAS No.: 2752009-40-6
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Tos-PEG1-O-CH2COOH (PROTAC Linker 28) is a PEG-based PROTAC linker can be used in the synthesis of PROTACs .
Cat. No.: HY-W572763
CAS No.: 2803338-37-4
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Tos-PEG6-acid is a PEG linker containing a tosyl group and a terminal carboxylic acid. The hydrophilic PEG spacer increases solubility in aqueous media. The tosyl group is a very good leaving group for nucleophilic substitution reactions. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. HATU) to form a stable amide bond.
Cat. No.: HY-W906996
CAS No.: 1800414-54-3
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PEG10-Tos is a PROTAC linker that can be used in the synthesis of PROTACs.
Cat. No.: HY-174922
CAS No.: 3075220-94-6
Cat. No.: HY-W574509
CAS No.: 2111895-60-2
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Tos-PEG2-acid (compound 30) is a PEG linker containing a tosyl group and a terminal carboxylic acid. Tos-PEG2-acid can react with primary amine groups .
Cat. No.: HY-W190738
CAS No.: 857892-34-3
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Azide-PEG8-Tos is a small PEG linker featuring an azide and a tosylate. Tosylates are good leaving groups which are easily displaced by nucleophiles while azide is a click chemistry motif which is used to react with terminal alkynes or strained cyclooctynes.
Cat. No.: HY-W572064
CAS No.: 81842-71-9
Synonyms: TOS-PR-OH
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3-Hydroxypropyl 4-methylbenzenesulfonate (TOS-PR-OH) is a PROTAC linker that can be used in the synthesis of PROTACs.
Cat. No.: HY-W800661
CAS No.: 2468714-93-2
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Tos-PEG3-methyl ester is a PEG linker with tosyl and methyl ester moieties. The tosyl group is a very good leaving group for nucleophilic substitution reactions. The hydrophilic PEG linker increases the water solubility of the compound. Methyl ester can be hydrolyzed under strong basic condition.
Cat. No.: HY-W190808
CAS No.: 778596-20-6
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Tos-PEG11-t-butyl ester is a PEG linker containing a t-butyl ester and a tosyl group. The hydrophilic PEG spacer increases solubility in aqueous media. The t-butyl protected carboxyl group can be deprotected under acidic conditions. The tosyl group is a very good leaving group for nucleophilic substitution reactions.
Cat. No.: HY-W591963
CAS No.: 1407974-54-2
Synonyms: TOS-pentane-azide
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5-Azidopentyl 4-methylbenzenesulfonate (Tos-pentane-azide) is a linker containing an azide group and a tosyl group. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. The tosyl group is a good leaving group for nucleophilic substitution reactions.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
