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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
102 Results for "
CD11b MPCs
" in MedChemExpress (MCE) Product Catalog:
Products (102)
102 Results for "CD11b MPCs" in MCE Product Catalog:
Cat. No.: HY-116509
CAS No.: 19878-10-5
Synonyms: Linoleic acid anilide; LAA
Research Areas:
Linoleylanilide (Linoleic acid anilide) is a Linoleic acid (HY-N0729) derivative. Linoleylanilide slightly inhibits the PMA (HY-18739)-induced expression of CD11b. Linoleylanilide inhibits serum LDH, GOT and GPT activities. Linoleylanilide decreases red cell counts and hemoglobin content .
Cat. No.: HY-RS18485
Target:
Research Areas:
Mpc1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Mpc1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS19353
Target:
Research Areas:
Mpc2 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Mpc2 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS25844
Target:
Research Areas:
Mpc2 Rat Pre-designed siRNA Set A contains three designed siRNAs for Mpc2 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-P86309
Synonyms: Integrin alpha-M; CD11 antigen-like family member B; CR-3 alpha chain; Cell surface glycoprotein MAC-1 subunit alpha; Leukocyte adhesion receptor MO1; Neutrophil adherence receptor; CD antigen CD11b;
Cat. No.: HY-U00212R
CAS No.: 86780-90-7
Synonyms: MPC1304 (Standard)
Target:
Research Areas:
Aranidipine (Standard) is the analytical standard of Aranidipine. This product is intended for research and analytical applications. Aranidipine (MPC1304) is a Ca 2+ channel antagonist with potent and long-lasting antihypertensive effects.
Cat. No.: HY-141677C
CAS No.: 1802909-50-7
Target:
Research Areas:
INCB059872 TFA is a potent, orally active, selective and irreversible Lysine-Specific Demethylase 1 (LSD1) inhibitor that achieves inhibitory activity through the formation of covalent FAD-adducts. INCB059872 TFA can inhibit cell proliferation and induce cell differentiation by upregulating the expression of myeloid differentiation markers CD86 and CD11b. INCB059872 TFA can be used for the research of myeloid leukemia .
Cat. No.: HY-P991772
Target:
Research Areas:
Cat. No.: HY-N0842R
CAS No.: 174022-42-5
Synonyms: PA-457 (Standard); MPC-4326 (Standard); YK FH312 (Standard)
Category:
Target:
Cat. No.: HY-121349
CAS No.: 28714-26-3
Category:
Target:
Cat. No.: HY-170571
Target:
Research Areas:
BE2647 is a selective inhibitor for mitochondrial pyruvate carrier (MPC) with an EC50 of 70 nM. BE2647 exhibits good metabolic stability in mouse liver microsomes. BE2647 can be used in research of metabolic diseases, non-alcoholic fatty liver disease (MASLD), or non-alcoholic steatohepatitis (MASH) .
Cat. No.: HY-P700759
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: ITGAM; Human Neutrophil Antigen 4; Prev. CR3A; HNA-4; Prev. CD11b; Integrin, Alpha M (Complement Component Receptor 3, Alpha; Also Known As CD11b (P170), Macrophage Antigen Alpha Polypeptide); Integrin Alpha-M; Neutrophil Adherence Receptor Alpha-M Subuni
Species:
Human
Source:
HEK293
Cat. No.: HY-106929B
CAS No.: 146957-32-6
Synonyms: CGS 25019C hydrochloride
Target:
Research Areas:
Moxilubant (CGS 25019C) hydrochloride is an orally active BLT1 antagonist. Moxilubant hydrochloride inhibits LTB4 signaling with a potency of 2-4 nM. Moxilubant hydrochloride blocks LTB4-induced neutrophil functions. Moxilubant hydrochloride inhibits ear edema and neutrophil infiltration in mice. Moxilubant hydrochloride can be used in research related to chronic obstructive pulmonary disease .
Cat. No.: HY-187551
CAS No.: 179487-75-3
Target:
Research Areas:
NPC-18915 free base is a neutrophil activation inhibitor. NPC-18915 free base inhibits CD11b/CD18-mediated neutrophil adhesion. NPC-18915 free base induces shedding of L-selectin on the neutrophil surface, thereby reducing endothelial cell adhesion. NPC-18915 free base inhibits calcium ionophore-induced LTB4 synthesis in neutrophils. NPC-18915 free base reduces the severity of TNBS-induced acute and recurrent colitis in rat experiments. NPC-18915 free base can be used in studies related to colitis .
Cat. No.: HY-108022R
CAS No.: 1133819-87-0
Synonyms: MSDC-0602 (Standard)
Research Areas:
Neurological Disease Metabolic Disease Inflammation/Immunology
Azemiglitazone (Standard) is the analytical standard of Azemiglitazone (HY-108022). This product is intended for research and analytical applications. Azemiglitazone (MSDC-0602) is an orally active thiazolidinedione (TZD) -like molecule, which binds to PPARγ with low binding and activating affinity. Azemiglitazone inhibits mitochondrial pyruvate carrier (MPC), which inhibits Alzheimer’s disease and diminishes nonalcoholic steatohepatitis (NASH) caused liver injury .
Cat. No.: HY-115499A
CAS No.: 1310540-31-8
Target:
Research Areas:
MPC-0767 free base is an orally active prodrug of Hsp90 inhibitor. MPC-0767 free base undergoes rapid biotransformation to the parent Hsp90 inhibitor MPC-3100 via enzyme-mediated luminal cleavage. MPC-0767 free base is applicable to the research of refractory and recurrent cancers .
Cat. No.: HY-100550R
CAS No.: 146062-49-9
Synonyms: Mitoglitazone (Standard); CAY10415 (Standard)
Research Areas:
MSDC 0160 (Standard) is the analytical standard of MSDC 0160 (HY-100550). This product is intended for research and analytical applications. MSDC 0160 (Mitoglitazone) is a mitochondrial target of thiazolidinediones (mTOT)-modulating insulin sensitizer and a modulator of mitochondrial pyruvate carrier (MPC). MSDC 0160 is a thiazolidinedione (TZD) with antidiabetic and neuroprotective activities. MSDC 0160 has the potential for Alzheimer′s disease .
Cat. No.: HY-W854727
CAS No.: 151872-44-5
N-Methylfulleropyrrolidine serves as an electron acceptor molecule characterized by its fullerene core and a nitrogen-free lone pair associated with the pyrrolidine ring. This compound can act as an intermediate in the synthesis of various functionalized fullerenes and plays a significant role in the development of opto-electronic devices. Comprehensive studies have been conducted on the photoinduced energy and electron transfer processes between oligothienylenevinylenes and N-Methylfulleropyrrolidine (MP-C60).
Cat. No.: HY-109593R
CAS No.: 1286279-29-5
Target:
Research Areas:
Cardiovascular Disease Inflammation/Immunology Endocrinology Cancer
BMS-813160 (Standard) is the analytical standard of BMS-813160 (HY-109593). This product is intended for research and analytical applications. BMS-813160 is a potent and selective CCR2/5 dual antagonist. BMS-813160 binds with CCR2 and CCR5 with IC50s of 6.2 and 3.6 nM, respectively. BMS-813160 can be used for the research of inflammation .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
