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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
104 Results for "
PKB
" in MedChemExpress (MCE) Product Catalog:
Products (104)
104 Results for "PKB" in MCE Product Catalog:
Cat. No.: HY-175068
Synonyms: Ins(1,3,4,5,6)P5 sodium
Research Areas:
D-myo-Inositol-1,3,4,5,6-pentaphosphate sodium (Ins(1,3,4,5,6)P5 sodium) is a small intracellular signaling molecule. D-myo-Inositol-1,3,4,5,6-pentaphosphate sodium inhibits the PI3K/Akt signaling pathway. D-myo-Inositol-1,3,4,5,6-pentaphosphate sodium inhibits Akt/PKB phosphorylation and kinase activity, inducing apoptosis in cancer cells. D-myo-Inositol-1,3,4,5,6-pentaphosphate sodium inhibits the formation of tubular structures in endothelial cells in an in vitro angiogenesis mouse model. D-myo-Inositol-1,3,4,5,6-pentaphosphate sodium can be used in research on ovarian cancer, lung cancer, breast cancer, and other cancers, as well as in cardiovascular and cerebrovascular diseases such as angiogenesis .
Cat. No.: HY-175042
Synonyms: Ins(1,3,4,5,6)P5 ammonium salt; 1,3,4,5,6-IP5 ammonium salt
D-myo-Inositol-1,3,4,5,6-pentaphosphate (ammonium salt) (Ins(1,3,4,5,6)P5 (ammonium salt)) is an isomer of inositol phosphate that acts as a small and soluble second messenger in the transmission of cellular signals. D-myo-Inositol-1,3,4,5,6-pentaphosphate (ammonium salt) can bind to the PH domain of Grp1 with a Kd of 590 nM. D-myo-Inositol-1,3,4,5,6-pentaphosphate (ammonium salt) can inhibit the phosphorylation and kinase activity of Akt/PKB, inducing apoptosis in ovarian, lung, and breast cancer cells. D-myo-Inositol-1,3,4,5,6-pentaphosphate (ammonium salt) exhibits antiangiogenic activity in vitro and blocks capillary tube formation of HUVEC. D-myo-Inositol-1,3,4,5,6-pentaphosphate (ammonium salt) exerts antitumor effects against cancer xenografts in nude mice .
Cat. No.: HY-P702632
Purity: ≥ 80%, as determined by reducing SDS-PAGE.
Synonyms: AKT2; Non-Specific Serine/Threonine Protein Kinase; AKT Serine/Threonine Kinase 2; Murine Thymoma Viral (V-Akt) Homolog-2; V-Akt Murine Thymoma Viral Oncogene Homolog 2; Rac Protein Kinase Beta; RAC-Beta Serine/Threonine-Protein Kinase; RAC Protein Kinase Beta; Protein Kinase B Beta; AKT2 Protein; Protein Kinase Akt-2; RAC-BETA; RAC-PK-Beta; PKBBETA; PKB Beta; HIHGHH; PKBB; PRKBB; Putative V-Akt Murine Thymoma Viral Oncoprotein 2; PKBβ
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-P706017
Purity: ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: AKT2; Non-Specific Serine/Threonine Protein Kinase; AKT Serine/Threonine Kinase 2; Murine Thymoma Viral (V-Akt) Homolog-2; V-Akt Murine Thymoma Viral Oncogene Homolog 2; Rac Protein Kinase Beta; RAC-Beta Serine/Threonine-Protein Kinase; RAC Protein Kinase Beta; Protein Kinase B Beta; AKT2 Protein; Protein Kinase Akt-2; RAC-BETA; RAC-PK-Beta; PKBBETA; PKB Beta; HIHGHH; PKBB; PRKBB; Putative V-Akt Murine Thymoma Viral Oncoprotein 2; PKBβ
Species:
Human
Source:
Sf9 insect cells
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
