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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
104 Results for "
PKB
" in MedChemExpress (MCE) Product Catalog:
Products (104)
104 Results for "PKB" in MCE Product Catalog:
Cat. No.: HY-19849
CAS No.: 736183-35-0
Synonyms: PGN 1531 free base
Target:
Research Areas:
BGC-20-1531 (PGN 1531) free base is a potent and selective prostanoid EP4 receptor antagonist, with a pKB of 7.6. BGC-20-1531 free base has the potential for the research of migraine headache .
Cat. No.: HY-10895R
CAS No.: 249889-64-3
Synonyms: SB 334867A (Standard)
Research Areas:
SB-334867 (Standard) is the analytical standard of SB-334867. This product is intended for research and analytical applications. SB-334867 (SB 334867A) is an excellent,selective and blood-brain barrier permeable orexin-1 (OX1) receptor antagonist, shows selectivity over OX2 (pKb=7.4), 100-fold over 5-HT2B, 5-HT2C with pKi values of 5.4 and 5.3, respectively . SB-334867 reduces ethanol consumption and inhibits the acquisition of morphine-induced sensitization to locomotor activity in vivo .
Cat. No.: HY-RS11402
Target:
Research Areas:
PTK2B Human Pre-designed siRNA Set A contains three designed siRNAs for PTK2B gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-103199
CAS No.: 39731-05-0
Synonyms: SDZ21009
Target:
Research Areas:
Carpindolol (SDZ21009) is a 5-HT1B receptor antagonist (pKd of 8.53 and pKB of 8.0) and a 5-HT1D receptor agonist (pEC50 of 5.91 and pKd of 6.37) .
Cat. No.: HY-B1621AR
CAS No.: 5870-29-1
Synonyms: DL-Cyclopentolate hydrochloride (Standard)
Target:
Research Areas:
Cyclopentolate (hydrochloride) (Standard) is the analytical standard of Cyclopentolate (hydrochloride). This product is intended for research and analytical applications. Cyclopentolate (DL-Cyclopentolate) hydrochloride is an Atropine-like muscarinic receptors antagonist with a pKB value of 7.8 (on the circular ciliary muscle). Cyclopentolate hydrochloride is an anti-muscarinic agent commonly used in the ophthalmologic practice .
Cat. No.: HY-120172
CAS No.: 169626-43-1
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Research Areas:
WAY-126299A is an orally active dual-acting 5-1ipoxygenase inhibitor (IC50: 12.2 μM) and leukotriene D4 antagonist (pKB: 6.4). WAY-126299A inhibits antigen-induced leukotriene-dependent bronchoconstriction. WAY-126299A can be used for research of asthma .
Cat. No.: HY-107563
CAS No.: 184576-87-2
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Research Areas:
ROS 234 is a potent H3 antagonist, with a pKB of 9.46 for Guinea-pig ileum H3-receptor, a pKi of 8.90 for Rat cerebral cortex H3-receptor, and a ED50 of 19.12 mg/kg (ip) in ex vivo of Rat cerebral cortex. ROS 234 diaplays poor central access .
Cat. No.: HY-107563A
CAS No.: 1781941-93-2
Target:
Research Areas:
ROS 234 dioxalate is a potent H3 antagonist, with a pKB of 9.46 for Guinea-pig ileum H3-receptor, a pKi of 8.90 for Rat cerebral cortex H3-receptor, and a ED50 of 19.12 mg/kg (ip) in ex vivo of Rat cerebral cortex. ROS 234 dioxalate diaplays poor central access .
Cat. No.: HY-N1401R
CAS No.: 112246-15-8
Category:
Panax ginseng C. A. Meyer Triterpenes Human Gut Microbiota Metabolites Terpenoids Plants Endogenous metabolite Araliaceae
Target:
Cat. No.: HY-10109A
Research Areas:
AS-605240 (potassium) is an orally active PI3Kγ inhibitor (IC50: 8 nM; Ki: 7.8 nM). AS-605240 (potassium) inhibits MCP-1- and CSF1-induced PKB phosphorylation (IC50 values are 0.181 and 0.550 µM, respectively). AS-605240 (potassium) reduces neutrophil recruitment in RANTES (CCL5)- and thioglycolate-induced peritonitis mouse models (EC50 values are 9.1 and 10 mg/kg, respectively). AS-605240 (potassium) ameliorates αCII-IA-induced arthritis in mice .
Cat. No.: HY-103152R
CAS No.: 144625-51-4
Target:
Research Areas:
GR 113808 (Standard) is the analytical standard of GR 113808. This product is intended for research and analytical applications. GR 113808 is a potent and highly selective 5-HT4 receptor antagonist (pKb= 8.8). GR 113808 shows 300-fold selectivity over 5-HT1A, 5-HT1B, 5-HT2A, 5-HT2C and 5-HT3 receptors .
Cat. No.: HY-P704088
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: AKT1; Protein Kinase B; AKT Serine/Threonine Kinase 1; PKB Alpha; RAC; V-Akt Murine Thymoma Viral Oncogene-Like Protein 1 Isoform 2; PKB; V-Akt Murine Thymoma Viral Oncogene-Like Protein 1; RAC-Alpha Serine/Threonine-Protein Kinase; Non-Specific Serine/Threonine Protein Kinase; RAC-PK-Alpha; AKT1m Transcript Variant 3; RAC-Alpha; AKT1m Transcript Variant 4; PRKBA; AKT1m Transcript Variant 2; AKT; AKT1m Transcript Variant 1; V-Akt Murine Thymoma Viral Oncogene Homolog 1; Rac Protein Kinase Alpha; Serine-Threonine Protein Kinase; PKB-ALPHA; Protein Kinase B Alpha; AKT1m; Proto-Oncogene C-Akt
Species:
Human
Source:
Sf9 insect cells
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
