2 Results for "

(S)-ML399

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "(S)-ML399" in MCE Product Catalog:

Cat. No.: HY-117948A
CAS No.: 1560968-51-5
Research Areas:  

Cancer

(S)-ML399 (Compound 18S) is the enantiomer of ML399 (HY-117948). (S)-ML399 acts as a Menin-MLL interaction inhibitor with an IC50 of 1400 nM. (S)-ML399 can be used to investigate acute leukemias with MLL translocations, including acute myeloid leukemia and acute lymphoblastic leukemia .
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Cat. No.: HY-103231
CAS No.: 389888-02-2
Target:  

iGluR

Research Areas:  

Neurological Disease

(S)-CPW 399 is a subtype-selective full agonist of AMPA receptors, with a 20-fold higher selectivity for GluA1 and GluA2 subunits over GluA3 and GluA4 subunits. (S)-CPW 399 can significantly increase the spontaneous firing rate (FR) of LC noradrenergic neurons by activating AMPA receptors containing GluA1 subunits. (S)-CPW 399 can be used for the study of neurological diseases .
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