1560968-51-5
Chemical Structure
(S)-ML399
- CAS No.: 1560968-51-5
- Formula:C27H28FN3O2
- Molecular Weight:445.53
InChIKey: YLADDJNCJBCBJE-MHZLTWQESA-N
SMILES: O[C@](C1CCN(CC1)CCCOC2=CC=C(C=C2)C#N)(C3=CC=CC=N3)C4=CC(F)=CC=C4
Biological Activity: (S)-ML399 (Compound 18S) is the enantiomer of ML399 (HY-117948). (S)-ML399 acts as a Menin-MLL interaction inhibitor with an IC50 of 1400 nM. (S)-ML399 can be used to investigate acute leukemias with MLL translocations, including acute myeloid leukemia and acute lymphoblastic leukemia[1].
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(S)-ML399 | (S)-ML399 (Compound 18S) is the enantiomer of ML399 (HY-117948). (S)-ML399 acts as a Menin-MLL interaction inhibitor with an IC50 of 1400 nM. (S)-ML399 can be used to investigate acute leukemias with MLL translocations, including acute myeloid leukemia and acute lymphoblastic leukemia. | |||||||||||||||||||||
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Keywords