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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
20 Results for "
(S)-thalidomide
" in MedChemExpress (MCE) Product Catalog:
Products (20)
20 Results for "(S)-thalidomide" in MCE Product Catalog:
Research Areas:
(S)-Thalidomide ((S)-(-)-Thalidomide) is the S-enantiomer of Thalidomide. (S)-Thalidomide has immunomodulatory, anti-inflammatory, antiangiogenic and pro-apoptotic effects . (S)-Thalidomide induces teratogenic effects by binding to cereblon (CRBN) .
Target:
Research Areas:
BODIPY FL thalidomide is a high-affinity and selective human cereblon (CRBN)-targeting fluorescent probe with a Kd of 3.6 nM. BODIPY FL thalidomide enables use as a probe in time-resolved fluorescence resonance energy transfer (TR-FRET) binding assays for cereblon ligands. BODIPY FL thalidomide supports development of highly sensitive, selective, stable cereblon TR-FRET binding assays (Ex/Em = 502/510 nm) .
Cat. No.: HY-W763812
CAS No.: 911109-85-8
Target:
Research Areas:
(S)-Thalidomide 4-fluoride is a CRBN E3 ligase ligand that can be used for synthesis of DeDPP4 (HY-182336).
Cat. No.: HY-W674436
CAS No.: 2357105-36-1
Target:
Research Areas:
(S)-Thalidomide-4-OH is the S-isomer of Thalidomide-4-OH (HY-103596). Thalidomide-4-OH (Cereblon ligand 2) is the Thalidomide-based Cereblon ligand used in the recruitment of CRBN protein. Thalidomide-4-OH (Cereblon ligand 2) can be connected to the ligand for protein by a linker to form PROTACs .
Cat. No.: HY-163230
Research Areas:
(1R,5S)-Thalidomide-3,8-diazabicyclo[3.2.1]octane-Boc is a conjugate of E3 ligase ligand and linker, consisting of Thalidomide (HY-14658) and the corresponding Linker. (1R,5S)-Thalidomide-3,8-diazabicyclo[3.2.1]octane-Boc can serve as a Cereblon ligand to recruit CRBN protein and serve as a key intermediate for the synthesis of complete PROTAC molecules.
Cat. No.: HY-163226
Research Areas:
(1R,5S)-Thalidomide-3,8-diazabicyclo[3.2.1]octane-(1R,4r)-cyclohexane-NH-Boc is a conjugate of E3 ligase ligand and linker, consisting of Thalidomide (HY-14658) and the corresponding Linker. (1R,5S)-Thalidomide-3,8-diazabicyclo[3.2.1]octane-(1R,4r)-cyclohexane-NH-Boc can serve as Cereblon ligand to recruit CRBN protein and serve as a key intermediate for the synthesis of complete PROTAC molecules.
Cat. No.: HY-157760
Research Areas:
(S)-Thalidomide-piperazine-pyrimidine-piperazine-C2-OH is a conjugate of E3 ligase ligand and linker, consisting of Thalidomide (HY-14658) and the corresponding Linker. (S)-Thalidomide-piperazine-pyrimidine-piperazine-C2-OH can serve as a Cereblon ligand to recruit CRBN proteins and serve as a key intermediate for the synthesis of complete PROTAC molecules.
Cat. No.: HY-168349
Research Areas:
(S)-Thalidomide-pyrrolidine-C-piperidine-Ph-NH2 is the coupling conjugate of the E3 ubiquitin ligase ligand and linker for NX-2127 (HY-153220) .
Cat. No.: HY-163225
Research Areas:
(S)-Thalidomide-piperazine-(1S,4r)-cyclohexane-NH-Boc is a conjugate of E3 ligase ligand and linker, consisting of Thalidomide (HY-14658) and the corresponding Linker. (S)-Thalidomide-piperazine-(1S,4r)-cyclohexane-NH-Boc can serve as a Cereblon ligand to recruit CRBN protein and serve as a key intermediate for the synthesis of complete PROTAC molecules.
Cat. No.: HY-157759
Research Areas:
(S)-Thalidomide-piperazine-pyrimidine-piperazine-C2-O-C2-OH is a conjugate of E3 ligase ligand and linker, consisting of Thalidomide (HY-14658) and the corresponding Linker. (S)-Thalidomide-piperazine-pyrimidine-piperazine-C2-O-C2-OH can serve as a Cereblon ligand to recruit CRBN proteins and serve as a key intermediate for the synthesis of complete PROTAC molecules.
Cat. No.: HY-163221
Research Areas:
(S)-Thalidomide-piperazine-(1S,4r)-cyclohexane-N(Me)-Boc is a conjugate of E3 ligase ligand and linker, consisting of Thalidomide (HY-14658) and the corresponding Linker. (S)-Thalidomide-piperazine-(1S,4r)-cyclohexane-N(Me)-Boc can serve as Cereblon ligand to recruit CRBN protein and serve as a key intermediate for the synthesis of complete PROTAC molecules.
Cat. No.: HY-157758
Research Areas:
(S)-Thalidomide-piperazine-pyrimidine-piperazine-C2-O-CH2-COO-C(CH3)3 is a conjugate of E3 ligase ligand and linker, consisting of Thalidomide (HY-14658) and the corresponding Linker . (S)-Thalidomide-piperazine-pyrimidine-piperazine-C2-O-CH2-COO-C(CH3)3 can serve as a Cereblon ligand to recruit CRBN protein and serve as a key intermediate for the synthesis of complete PROTAC molecules.
Cat. No.: HY-W457158
CAS No.: 172333-29-8
Target:
Research Areas:
(S)-Thalidomide-5-OH is an E3 ubiquitin ligase cereblon (CRBN) ligand used to recruit the cereblon protein. (S)-Thalidomide-5-OH can be linked to a target protein ligand via a linker to form a PROTAC.
Cat. No.: HY-161183
Research Areas:
(S)-Thalidomide-O-(1S,3r)-C4H4-N(Me)-Pip-C2-O-C-boc is a conjugate of E3 ligase ligand and linker, consisting of Thalidomide (HY-14658) and the corresponding Linker. (S)-Thalidomide-O-(1S,3r)-C4H4-N(Me)-Pip-C2-O-C-boc can serve as a Cereblon ligand to recruit CRBN protein and serve as a key intermediate for the synthesis of complete PROTAC molecules.
Cat. No.: HY-W998236
CAS No.: 2937062-27-4
Research Areas:
(S)-Thalidomide-5-fluoro-6-piperazin besylate is an E3 ligase ligand-linker conjugate containing a CRBN-based ligand and linker, which can be used to synthesize PROTAC.
Cat. No.: HY-157588
Research Areas:
E3 ligase Ligand-Linker Conjugate 30 is a conjugate of E3 ligase ligand and linker, consisting of Thalidomide (HY-14658) and the corresponding Linker. E3 ligase Ligand-Linker Conjugate 30 can serve as Cereblon ligand to recruit CRBN protein and serve as a key intermediate for the synthesis of complete PROTAC molecules.
Cat. No.: HY-W998237
CAS No.: 2937046-84-7
Research Areas:
(S)-Thalidomide-piperazin besylate is an E3 ligase ligand-linker conjugate containing a CRBN-based ligand and linker, which can be used to synthesize PROTAC.
Cat. No.: HY-W998308
CAS No.: 2782051-26-5
Research Areas:
(S)-Thalidomide-azetidine-O-Pip is an E3 ligase ligand-linker conjugate containing a CRBN-based ligand and linker, which can be used to synthesize PROTAC.
Cat. No.: HY-182337
Research Areas:
(S)-Thalidomide 4-fluoride is an E3 ligase linker conjugate that can be used for the synthesis of DeDPP4 (HY-182336) .
Cat. No.: HY-163961
Research Areas:
(S)-Thalidomide-NH-cyclohexane-NH-Ph-NH2 (Compound C63) is the E3 ligase + linker of (HY-163938) PROTAC, which contains Thalidomide-based cereblon ligand and 1 linker and can be used for synthesis PROTAC .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
