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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
8 Results for "
1,2,4-oxadiazoles
" in MedChemExpress (MCE) Product Catalog:
Products (8)
8 Results for "1,2,4-oxadiazoles" in MCE Product Catalog:
1
1 Cited Publications
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DDO-7263, a 1,2,4-Oxadiazole derivative, is a potent Nrf2-ARE activator. DDO-7263 upregulates Nrf2 through binding to Rpn6 to block the assembly of 26S proteasome and the subsequent degradation of ubiquitinated Nrf2. DDO-7263 induces Nrf2 translocation into the nucleus. DDO-7263 inhibits of NLRP3 inflammasome activation. DDO-7263 exerts anti-inflammatory activity and has the potential for neurodegenerative diseases research, such as Parkinson's disease (PD) .
Cat. No.: HY-167890
CAS No.: 1839120-27-2
Flufenoxadiazam is a commercially available 1,2,4-oxadiazole-containing fungicide produced by BASF, with activity against Phakopsora pachyrhizi and Puccinia triticina. Flufenoxadiazam contains a trifluoromethyloxadiazole substructure essential for its activity. Flufenoxadiazam can be used for the research of soybean rust and corn rust .
Cat. No.: HY-146753
CAS No.: 2758387-58-3
HIV-1 inhibitor-20 is a potent HIV-1 inhibitor by non-classical isosteric replacement of amide to 1,2,4-oxadiazoles .
Cat. No.: HY-P10472
CAS No.: 134457-28-6
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Cat. No.: HY-143242
CAS No.: 1301638-42-5
Category:
Alkaloids Microorganisms Other Alkaloids Marine natural products Other Diseases Disease Research Fields Marine microorganism
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Cat. No.: HY-W190972
CAS No.: 20844-48-8
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3-(3-Nitrophenyl)-5-phenyl-1,2,4-oxadiazole is a PEG derivative containing a tert-butyl ester and an azide group .
Cat. No.: HY-W291147
CAS No.: 27199-40-2
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Pifexole is a biologically active 3,5-disubstituted-1,2,4-oxadiazole compound. Pifexole exhibits antispasmodic and muscle relaxant activities, with no effect on monosynaptic knee-jerk reflex. Pifexole can be used in studies related to muscle relaxation and spasm .
Cat. No.: HY-181750
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NAT8L-IN-2 (compound 4u) is a submicromolar NAT8L inhibitor based on an N-acylated (piperidin-3-ylmethyl)-1,2,4-oxadiazole scaffold, with an IC50 value of 0.4 μM against NAT8L. NAT8L-IN-2 can be used for the research of canavan disease .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
