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160807-49-8

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1 Results for "160807-49-8" in MCE Product Catalog:

4
4 Cited Publications
Cat. No.: HY-19807
CAS No.: 160807-49-8
Synonyms: Indirubin-3'-oxime
Target:  

GSK-3 CDK Lipoxygenase

Research Areas:  

Cancer

Indirubin-3'-monoxime is a potent GSK-3β inhibitor, and weakly inhibits 5-Lipoxygenase, with IC50s of 22 nM and 7.8-10 µM, respectively; Indirubin-3'-monoxime also shows inhibitory activities against CDK5/p25 and CDK1/cyclin B, with IC50s of 100 and 180 nM.
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