160807-49-8
160807-49-8
Chemical Structure
Indirubin-3'-monoxime
Synonym(s): Indirubin-3'-oxime
- CAS No.: 160807-49-8
- Formula:C16H11N3O2
- Molecular Weight:277.28
IUPAC Name: (2E,3E)-3-(hydroxyimino)-[2,3'-biindolinylidene]-2'-one
InChIKey: HBDSHCUSXQATPO-OIXOFKMYSA-N
SMILES: O=C1NC2=C(C=CC=C2)/C1=C3NC4=C(C=CC=C4)C\3=N/O
Biological Activity: Indirubin-3'-monoxime is a potent GSK-3β inhibitor, and weakly inhibits 5-Lipoxygenase, with IC50s of 22 nM and 7.8-10 µM, respectively; Indirubin-3'-monoxime also shows inhibitory activities against CDK5/p25 and CDK1/cyclin B, with IC50s of 100 and 180 nM.
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Indirubin-3'-monoxime | 99.80% | Indirubin-3'-monoxime is a potent GSK-3β inhibitor, and weakly inhibits 5-Lipoxygenase, with IC50s of 22 nM and 7.8-10 µM, respectively; Indirubin-3'-monoxime also shows inhibitory activities against CDK5/p25 and CDK1/cyclin B, with IC50s of 100 and 180 nM. | ||||||||||||||||||||
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