2 Results for "

1802678-42-7

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "1802678-42-7" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-103637A
CAS No.: 1802678-42-7
Purity:  98.39%
Synonyms: VTP-43742 hydrochloride
Target:  

ROR Interleukin Related

Research Areas:  

Inflammation/Immunology

Vimirogant hydrochloride (VTP-43742 hydrochloride) is a potent, selective, and orally active RORγt inhibitor with a Ki of 3.5 nM for binding to RORγt. VTP-43742 blocks Th17 cell differentiation and reduces IL-17A production by inhibiting RORγt-mediated transcriptional activity, thereby suppressing the RORγt/Th17/IL-17 inflammatory axis. VTP-43742 can be used for research on autoimmune diseases and inflammation-related diseases .
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Cat. No.: HY-103637
CAS No.: 1802706-04-2
Synonyms: VTP-43742
Target:  

ROR Interleukin Related

Research Areas:  

Inflammation/Immunology

Vimirogant (VTP-43742) is a potent, selective, and orally active RORγt inhibitor with a Ki of 3.5 nM for binding to RORγt. VTP-43742 blocks Th17 cell differentiation and reduces IL-17A production by inhibiting RORγt-mediated transcriptional activity, thereby suppressing the RORγt/Th17/IL-17 inflammatory axis. VTP-43742 can be used for research on autoimmune diseases and inflammation-related diseases .
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