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2'-AA (Standard)

" in MedChemExpress (MCE) Product Catalog:

17

Inhibitors & Agonists

1

Biochemical Assay Reagents

4

Natural
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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-15414R
    Vortioxetine (Standard)

    Lu AA 21004 (Standard)

    		 Reference Standards 5-HT Receptor Serotonin Transporter Neurological Disease Cancer
    Vortioxetine (Standard) is an analytical standard for Vortioxetine. This product is intended for research and analytical applications. Vortioxetine (Lu AA 21004) is an antagonist of 5-HT3A and 5-HT7 receptors (Ki: 3.7 nM, 19 nM) and an inhibitor of serotonin transporter (SERT) (Ki: 1.6 nM), as well as a 5-HT1A agonist and a partial 5-HT1B agonist (Ki: 15 nM, 33 nM) .
    Vortioxetine (Standard)
  • HY-B0774R
    Seratrodast (Standard)

    AA 2414 (Standard)

    		 Ferroptosis JNK MDM-2/p53 Prostaglandin Receptor Reference Standards Reactive Oxygen Species (ROS) Neurological Disease Inflammation/Immunology Endocrinology Cancer
    Seratrodast (Standard) is the analytical standard of Seratrodast. This product is intended for research and analytical applications. Seratrodast (AA 2414), an orally active antiasthmatic agent, is a thromboxane A2 receptor (TP) antagonist and ferroptosis inhibitor. Seratrodast reduces lipid ROS production, modulates the systemic xc-/GSH/GPX4 axis, and inhibits JNK phosphorylation and p53 expression. Seratrodast exhibits anti-asthmatic and anti-epileptic activity .
    Seratrodast (Standard)
  • HY-15414AR
    Vortioxetine hydrobromide (Standard)

    Lu AA21004 hydrobromide (Standard)

    		 5-HT Receptor Serotonin Transporter Reference Standards Neurological Disease Cancer
    Vortioxetine (hydrobromide) (Standard) is the analytical standard of Vortioxetine (hydrobromide). This product is intended for research and analytical applications. Vortioxetine (Lu AA 21004) hydrobromide is an antagonist of 5-HT3A and 5-HT7 receptors (Ki: 3.7 nM, 19 nM) and an inhibitor of 5-hydroxytryptamine transporter (SERT) (Ki: 1.6 nM), as well as a 5-HT1A agonist and a partial 5-HT1B agonist (Ki: 15 nM, 33 nM) .
    Vortioxetine hydrobromide (Standard)
  • HY-B0713R
    Amlexanox (Standard)

    AA673 (Standard); Amoxanox (Standard); CHX3673 (Standard)

    		 Reference Standards IKK Metabolic Disease
    Amlexanox (Standard) is the analytical standard of Amlexanox. This product is intended for research and analytical applications. Amlexanox (AA673; Amoxanox; CHX3673) is a specific inhibitor of IKKε and TBK1, and inhibits the IKKε and TBK1 activity determined by MBP phosphorylation with an IC50 of approximately 1-2 μM.
    Amlexanox (Standard)
  • HY-N3027R
    Soyasaponin Aa (Standard)

    		Reference Standards PPAR Reactive Oxygen Species (ROS) Metabolic Disease
    Soyasaponin Aa (Standard) is the analytical standard of Soyasaponin Aa (HY-N3027). Soyasaponin Aa is a soyasaponin that can be found in soy. Soyasaponin Aa suppresses PPARγ transcriptional activity, reduces PPARγ and C/EBPα expression, inhibits adipocyte differentiation and lipid accumulation, and reduces adipogenic marker gene expression. Soyasaponin Aa reduces hydrogen peroxide-induced reactive oxygen species (ROS) production and malondialdehyde levels. Soyasaponin Aa exhibits cellular antioxidant activity. Soyasaponin Aa can be used for the research of obesity .
    Soyasaponin Aa (Standard)
  • HY-12886R
    Docebenone (Standard)

    AA 861 (Standard)

    		 Lipoxygenase Ferroptosis Reference Standards Inflammation/Immunology
    Docebenone (Standard) is the analytical standard of Docebenone. This product is intended for research and analytical applications. Docebenone (AA 861) is a potent, selective and orally active 5-LO (5-lipoxygenase) inhibitor.
    Docebenone (Standard)
  • HY-108283R
    Trepibutone (Standard)

    AA 149 (Standard); Supacal (Standard)

    		 Calcium Channel Reference Standards Inflammation/Immunology
    Trepibutone (Standard) is the analytical standard of Trepibutone. This product is intended for research and analytical applications. Trepibutone (AA 149) increases secretion of bile and pancreatic juice, and accelerates flaccidity of the smooth muscle in the gastrointestinal tract. Trepibutone can be used for the research of cholecystitis and functional gastrointestinal disorders .
    Trepibutone (Standard)
  • HY-158461
    Alpha-Gal standard, 2-AA labelled

    Galactose-alpha-1,3-galactose, 2-AA labelled

    		 Biochemical Assay Reagents Others
    Alpha-Gal standard, 2-AA labelled (Galactose-alpha-1,3-galactose, 2-AA labelled) is a N-polysaccharide protein and a multifunctional fluorescent linker. The resulting conjugates exhibit high sensitivity and specificity by mimicking the antennal elements of N-glycans .
    Alpha-Gal standard, 2-AA labelled
  • HY-N0026R
    2'-Acetylacteoside (Standard)

    2'-AA (Standard)

    		 Reference Standards Monoamine Oxidase RANKL/RANK TNF Receptor NF-κB IKK Cardiovascular Disease Neurological Disease Metabolic Disease
    2'-Acetylacteoside (Standard) is the analytical standard of 2'-Acetylacteoside (2'-AA) (HY-N0026). This product is intended for research and analytical applications. 2'-Acetylacteoside is a natural compound with oral activity and blood-brain barrier permeability. 2'-Acetylacteosideexhibits MAO‑B inhibitory activity (IC50 = 17.71 μM, Ki = 13.81 μM). 2'-Acetylacteoside downregulates the expression of RANK, TRAF6, NF‑κB, NFATc1 and IKKβ, disrupts the RANKL/RANK interaction, blocks downstream signaling pathways, and increases the level of phosphorylated Akt. 2'-Acetylacteoside possesses potent anti-osteoclastogenic, anti-bone resorptive, pro-neurogenic, neuroprotective and antioxidant activities. 2'-Acetylacteoside can be used in the research of osteoporosis, ischemic stroke and Parkinson's disease .
    2'-Acetylacteoside (Standard)
  • HY-B1419R
    Salicyl alcohol (Standard)

    2-Hydroxybenzyl alcohol (Standard); Saligenin (Standard)

    		 Drug Intermediate Reference Standards Others
    Soyasaponin Aa (Standard) is the analytical standard of Soyasaponin Aa. This product is intended for research and analytical applications. Soyasaponin Aa is a soyasaponin that exerts an anti-obesity effect in 3T3-L1 adipocytes through downregulation of peroxisome proliferator-activated receptor γ (PPARγ) .
    Salicyl alcohol (Standard)
  • HY-W268542R
    4-Acetylaminoantipyrine (Standard)

    		Reference Standards COX SOD PGE synthase Inflammation/Immunology Cancer
    4-Acetylaminoantipyrine (Standard) is the analytical standard of 4-Acetylaminoantipyrine. This product is intended for research and analytical applications. 4-Acetylaminoantipyrine (4-AA) is a derivative of antipyrine (HY-B0171). 4-Acetylaminoantipyrine acts as a PGE2-dependent blocker and inhibitor of cyclooxygenase (COX) . 4-Acetylaminoantipyrine can inhibit Cu/ZnSOD . 4-Acetylaminoantipyrine can spontaneously bind with bovine serum albumin (BSA) and alter its conformation .
    4-Acetylaminoantipyrine (Standard)
  • HY-N0511R
    Aristolochic acid B (Standard)

    Aristolochic acid II (Standard)

    		 Reference Standards DNA Alkylator/Crosslinker Cancer
    Aristolochic acid B (Standard) is the analytical standard of Aristolochic acid B (HY-N0511). This product is intended for research and analytical applications. Aristolochic acid B (Aristolochic Acid II) is an orally active major component of aristolochic acid (AA). Aristolochic acid B can be isolated from plants of the genus Aristolochica. Aristolochic acid B forms DNA adducts. Aristolochic acid B is mutagenic. Aristolochic acid B exhibits a greater carcinogenic risk in vivo than Aristolochic acid I (HY-N0510) .
    Aristolochic acid B (Standard)
  • HY-101755R
    Tedatioxetine hydrobromide (Standard)

    Lu AA24530 hydrobromide (Standard)

    		 Reference Standards 5-HT Receptor Adrenergic Receptor Neurological Disease Endocrinology
    Tedatioxetine hydrobromide (Standard) (Lu AA24530 hydrobromide (Standard)) is the analytical standard of Tedatioxetine hydrobromide (HY-101755). This product is intended for research and analytical applications. Tedatioxetine (Lu AA24530) hydrobromide acts as a serotonin and norepinephrine (NE)-preferring triple reuptake inhibitor (TRI) and 5-HT2A, 5-HT2C, 5-HT3 and α1A-adrenergic receptor antagonist . ,
    Tedatioxetine hydrobromide (Standard)
  • HY-101518R
    Alrizomadlin (Standard)

    APG-115 (Standard); AA-115 (Standard)

    		 MDM-2/p53 Reference Standards E1/E2/E3 Enzyme Apoptosis Cancer
    Alrizomadlin (Standard) is the analytical standard of Alrizomadlin (HY-101518). This product is intended for research and analytical applications. Alrizomadlin (APG-115) is an orally active MDM2 protein inhibitor binding to MDM2 protein with IC50 and Ki values of 3.8 nM and 1 nM, respectively . Alrizomadlin blocks the interaction of MDM2 and p53 and induces cell-cycle arrest and apoptosis in a p53-dependent manner .
    Alrizomadlin (Standard)
  • HY-105872R
    Trifenagrel (Standard)

    		Reference Standards COX Cardiovascular Disease
    Trifenagrel (Standard) is the analytical standard of Trifenagrel (HY-105872). This product is intended for research and analytical applications. Trifenagrel is an orally active platelet aggregation inhibitor that inhibits the inducing effects of arachidonic acid (AA) and collagen. The ED50s of trifenagrel for inhibiting AA- and collagen-induced platelet aggregation in guinea pigs were 1.4 mg/kg and 9.4 mg/kg, respectively .
    Trifenagrel (Standard)
  • HY-106200R
    CJ-13,610 (Standard)

    		Reference Standards Lipoxygenase Inflammation/Immunology
    CJ-13,610 (Standard) is the analytical standard of CJ-13,610 (HY-106200). This product is intended for research and analytical applications. CJ-13,610, a nonredox-type 5-LO inhibitor, dose dependently suppresses 5-LO product formation in ionophore A23187-stimulated PMNL in the absence of exogenous AA with an IC50 of about 70 nM . PMNL: polymorphonuclear leukocytes; AA: arachidonic acid
    CJ-13,610 (Standard)
  • HY-103162R
    ANR94 (Standard)

    		Reference Standards Adenosine Receptor Neurological Disease
    ANR94 (Standard) is the analytical standard of ANR94 (HY-103162). This product is intended for research and analytical applications. ANR94 is a potent and selective adenosine A2A receptor (AA2AR) antagonist with an Ki of 46 nM for hAA2AR. ANR94 has the potential for the research of Parkinson's disease .
    ANR94 (Standard)

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