179420-17-8
179420-17-8
Chemical Structure
CJ-13,610
- CAS No.: 179420-17-8
- Formula:C22H23N3O2S
- Molecular Weight:393.50
IUPAC Name: 4-(3-((4-(2-methyl-1H-imidazol-1-yl)phenyl)thio)phenyl)tetrahydro-2H-pyran-4-carboxamide
InChIKey: VPTONMHDLLMOOV-UHFFFAOYSA-N
SMILES: NC(C1(C2=CC(SC3=CC=C(N4C(C)=NC=C4)C=C3)=CC=C2)CCOCC1)=O
Biological Activity: CJ-13,610, a nonredox-type 5-LO inhibitor, dose dependently suppresses 5-LO product formation in ionophore A23187-stimulated PMNL in the absence of exogenous AA with an IC50 of about 70 nM[1]. PMNL: polymorphonuclear leukocytes; AA: arachidonic acid
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CJ-13,610 | 98.10% | CJ-13,610, a nonredox-type 5-LO inhibitor, dose dependently suppresses 5-LO product formation in ionophore A23187-stimulated PMNL in the absence of exogenous AA with an IC50 of about 70 nM. PMNL: polymorphonuclear leukocytes; AA: arachidonic acid | ||||||||||||||||||||
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CJ-13,610 (Standard) | ≥98% | CJ-13,610 (Standard) is the analytical standard of CJ-13,610 (HY-106200). This product is intended for research and analytical applications. CJ-13,610, a nonredox-type 5-LO inhibitor, dose dependently suppresses 5-LO product formation in ionophore A23187-stimulated PMNL in the absence of exogenous AA with an IC50 of about 70 nM. PMNL: polymorphonuclear leukocytes; AA: arachidonic acid | ||||||||||||||||||||
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References
Keywords
