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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
6 Results for "
2,3-Oxidosqualene
" in MedChemExpress (MCE) Product Catalog:
Products (6)
6 Results for "2,3-Oxidosqualene" in MCE Product Catalog:
1
Research Areas:
2,3-Oxidosqualene (Squalene oxide) is a sterol biosynthesis precursor intermediate.2,3-Oxidosqualene participates in cyclization pathways that form sterols and triterpenes, and contributes to introduction of their characteristic 3-hydroxyl group.2,3-Oxidosqualene forms metabolically from squalene in rat liver homogenates under sterol synthesis conditions.2,3-Oxidosqualene converts to sterols including cholesterol, lathosterol, and lanost-8-en-3β-ol in rat liver homogenates under anaerobic conditions .
Target:
Research Areas:
BIBB 515 is a potent, selective and orally active 2,3-oxidosqualene cyclase (OSC) inhibitor with ED50 values of 0.2-0.5 mg/kg and 0.36-33.3 mg/kg in rats and mice (1-5 hours), respectively. BIBB 515 exerts lipid-lowering effect mainly by inhibiting the production of low-density lipoprotein (LDL) .
Cat. No.: HY-114296S
Synonyms: Squalene oxide-d6
Cat. No.: HY-W743885
CAS No.: 54910-48-4
Synonyms: (3S)-Squalene oxide; (S)-2,3-Epoxysqualene
Category:
Target:
Cat. No.: HY-187586
CAS No.: 104905-12-6
Target:
Research Areas:
Mdl 28815 is an inhibitor of Sterol-delta 14-reductase and 2,3-oxido-squalene cyclase, with IC50 values of 0.07 μM and 2 μM, respectively. Mdl 28815 blocks cholesterol biosynthesis and causes the accumulation of specific sterol metabolites. Mdl 28815 is applicable to research related to hypercholesterolemia .
Cat. No.: HY-P72309
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: LSS; 2,3-Epoxysqualene--Lanosterol Cyclase; Lanosterol Synthase; 2,3-Epoxysqualene-Lanosterol Cyclase; OSC; Oxidosqualene-Lanosterol Cyclase; Lanosterol Synthase (2,3-Oxidosqualene-Lanosterol Cyclase); CTRCT44; Oxidosqualene--Lanosterol Cyclase; HYPT14; H
Species:
Human
Source:
P. pastoris
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
