Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
6 Results for "
5'-GMP analogue
" in MedChemExpress (MCE) Product Catalog:
Products (6)
6 Results for "5'-GMP analogue" in MCE Product Catalog:
Cat. No.: HY-W013111
CAS No.: 102783-74-4
Synonyms: dGDP trisodium; 2'-Deoxyguanosine-5'-diphosphate trisodium
Research Areas:
2′-Deoxy-GDP (dGDP) trisodium, a guanosine monophosphate (GMP) analogue, is a hypoxanthine phosphoribosyltransferase (HGPRT) inhibitor with an IC50 of 12.5 μM. HGPRT is a central enzyme in the purine recycling pathway of all protozoan parasites .
Target:
Research Areas:
Ebselen oxide, the selenone analogue of Ebselen, covalently modifies diguanylate cyclase (DGC) to inhibit c-di-GMP-receptor interactions and reduces DGC activity. Ebselen oxide also inhibits alginate production (IC50=14 μM) by Pseudomonas aeruginosa. Ebselen oxide inhibits HDAC1, HDAC3, HDAC4, HDAC5, HDAC6, HDAC7, HDAC8, and HDAC9 (IC50 ranging from 0.2 to 4.7 μM) .
Cat. No.: HY-101445G
CAS No.: 53188-07-1
Cat. No.: HY-131817
CAS No.: 76310-16-2
Target:
Research Areas:
5'-GMPS is an analogue of 5'-GMP and a substrate, competitive inhibitor or regulator of enzymes that interact with 5'-GMP. 5'-GMPS is suitable as a primer of RNA synthesis by T7 RNA polymerase .
Cat. No.: HY-134242
CAS No.: 74686-78-5
Synonyms: 6-Thioguanosine monophosphate disodium; 6-Thio-GMP disodium
Target:
Research Areas:
6-T-5'-GMP disodium is an analogue of guanosine-5'-O-monophosphate (5'-GMP) and a metabolite of an immunosuppressive drug, azathioprine (HY-B0256) .
Cat. No.: HY-134242A
CAS No.: 15867-02-4
Synonyms: 6-Thioguanosine monophosphate; 6-Thio-GMP
Target:
Research Areas:
6-T-5'-GMP (6-Thioguanosine monophosphate) is an analogue of guanosine-5'-O-monophosphate (5'-GMP) and a metabolite of an immunosuppressive drug, Azathioprine (HY-B0256) .
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
