127 Results for "

5-Amino-

" in MedChemExpress (MCE) Product Catalog:
Products (127)

127 Results for "5-Amino-" in MCE Product Catalog:

20
20 Publications Verification
Cat. No.: HY-N0305
CAS No.: 5451-09-2
Synonyms: 5-ALA hydrochloride; δ-Aminolevulinic acid hydrochloride; 5-Amino-4-oxopentanoic acid hydrochloride
5-Aminolevulinic acid (5-ALA; δ-Aminolevulinic acid; 5-Amino-4-oxopentanoic acid) hydrochloride is an orally active heme precursor. 5-Aminolevulinic acid hydrochloride promotes aerobic energy metabolism and increases ATP levels by enhancing the activity of cytochrome c oxidase. 5-Aminolevulinic acid hydrochloride enhances LPS-induced proinflammatory cytokine production and gene activation, and restores the phagocytic activity and ROS generation capacity of neutrophils. 5-Aminolevulinic acid hydrochloride selectively accumulates protoporphyrin IX in tumor cells; as a photosensitizer and radiosensitizer, it induces ROS burst upon light or X-ray irradiation to inhibit tumor growth. 5-Aminolevulinic acid hydrochloride can be applied to the research of septic shock, melanoma, and cancer radiotherapy .
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20
20 Publications Verification
Cat. No.: HY-W000450
CAS No.: 106-60-5
Synonyms: 5-ALA; δ-Aminolevulinic acid; 5-Amino-4-oxopentanoic acid
5-Aminolevulinic acid (5-ALA; δ-Aminolevulinic acid; 5-Amino-4-oxopentanoic acid) is an orally active heme precursor. 5-Aminolevulinic acid promotes aerobic energy metabolism and increases ATP levels by enhancing the activity of cytochrome c oxidase. 5-Aminolevulinic acid enhances LPS-induced proinflammatory cytokine production and gene activation, and restores the phagocytic activity and ROS generation capacity of neutrophils. 5-Aminolevulinic acid selectively accumulates protoporphyrin IX in tumor cells; as a photosensitizer and radiosensitizer, it induces ROS burst upon light or X-ray irradiation to inhibit tumor growth. 5-Aminolevulinic acid can be applied to the research of septic shock, melanoma, and cancer radiotherapy .
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4
4 Cited Publications
Cat. No.: HY-P2336A
Target:  

Melanocortin Receptor

Research Areas:  

Cancer

CCZ01048 TFA, a α-MSH analogue, exhibits high binding affinity to melanocortin 1 receptor (MC1R) with a Ki of 0.31 nM. CCZ01048 TFA shows rapid internalization into B16F10 melanoma cells and high in vivo stability. CCZ01048 TFA is a promising candidate for PET imaging of malignant melanoma .
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1
1 Cited Publications
Cat. No.: HY-41461
CAS No.: 360-97-4
Synonyms: 5-Aminoimidazole-4-carboxamide; AICA
5-Amino-3H-imidazole-4-Carboxamide (5-Aminoimidazole-4-carboxamide; AICA) is an important precursor for the synthesis of purines in general and of the nucleobases adenine and guanine in particular .
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1
1 Cited Publications
Cat. No.: HY-41461A
CAS No.: 72-40-2
Synonyms: 5-Aminoimidazole-4-carboxamide hydrochloride; AICA hydrochloride
Category:  

Microorganisms

Target:  

Endogenous Metabolite

5-Amino-3H-imidazole-4-Carboxamide (AICA) hydrochloride is an important precursor for the synthesis of purines in general and of the nucleobases adenine and guanine in particular .
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1
1 Cited Publications
Cat. No.: HY-105055
CAS No.: 77327-05-0
Purity:  99.95%
Didemnin B is a depsipeptide extracted from the marine tunicate Trididemnin cyanophorum. Didemnin B can be used for the research of cancer .
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Cat. No.: HY-W001023
CAS No.: 13207-66-4
Synonyms: 5A8HQ; 5AHQ
Target:  

Proteasome NF-κB

Research Areas:  

Cancer

5-Amino-8-hydroxyquinoline (5A8HQ; 5AHQ) is an orally active non-competitive 20S proteasome inhibitor. 5-Amino-8-hydroxyquinoline can inhibit NF-κB activity and induce cancer cells death and shows low cytotoxicity towards normal hematopoietic cells. 5-Amino-8-hydroxyquinoline can be used for the research of cancer, such as leukemia .
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Cat. No.: HY-P5481
CAS No.: 1807943-24-3
Target:  

Peptides

Research Areas:  

Others

DABCYL-LPETG-EDANS is a biological active peptide. (This 5-amino acid peptide is a sortase substrate, C-terminal sorting signal. Sortase cleaves surface proteins at the LPXTG motif and catalyzes the formation of an amide bond between the carboxyl group of threonine and the amino group of cell-wall crossbridges. Sortases are a family of Gram-positive transpeptidases responsible for anchoring surface protein virulence factors to the peptidoglycan cell wall layer. Cleavage of this FRET substrate by sortase reveals the fluorescent signal, Abs/Em = 340/490 nm.)
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Cat. No.: HY-W012971
CAS No.: 2508-29-4
Research Areas:  

Others

5-Amino-1-pentanol is a linker containing a hydroxyl group and amine group. The hydroxyl group enables further derivatization or replacement with other reactive functional groups. The amine group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc.
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Cat. No.: HY-131818
CAS No.: 14365-44-7
Purity:  96.40%
Synonyms: NH2dAdo; Nsc 238990
Research Areas:  

Cancer

5'-Amino-5'-deoxyadenosine (NH2dAdo; Nsc 238990) is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
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Cat. No.: HY-W011203
CAS No.: 6610-42-0
Research Areas:  

Others

(S)-2-(5-Amino-2-(((benzyloxy)carbonyl)amino)-5-oxopentanamido)acetic acid is a Glycine (HY-Y0966) derivative .
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Cat. No.: HY-W074975
CAS No.: 14949-00-9
Synonyms: 5-Amino-1,3,4-thiadiazole-2-sulfonamide
Target:  

Carbonic Anhydrase

Research Areas:  

Cancer

CL 5343 (5-Amino-1,3,4-thiadiazole-2-sulfonamide) is a selective inhibitor of carbonic anhydrase B (HCA-B) and isoforms I, II, IV, and VII. CL 5343 has a Ki of 7.9 nM for hCA II. CL 5343 acts as a CA9 ligand to achieve targeted delivery of maytansine to the cell membrane of SKRC52 renal cancer cells. CL 5343 is useful in the development of therapeutics for diseases associated with CA overactivity, such as glaucoma, epilepsy, and cancer .
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Cat. No.: HY-66048
CAS No.: 3430-14-6
Synonyms: 5-Amino-2-methylpyridine
5-Amino-2-picoline (5-Amino-2-methylpyridine) is a biochemical reagent that can be used as a biological material or organic compound for life science related research. 5-Amino-2-picoline is also an important intermediate and can be used in the synthesis of other active compounds .
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Cat. No.: HY-W057815
CAS No.: 863600-81-1
Target:  

PROTAC Linkers

Research Areas:  

Cancer

cis-5-Amino-2-Boc-hexahydro-cyclopenta[c]pyrrole is a PROTAC linker that can be used in the synthesis of PROTACs.
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Cat. No.: HY-78055
CAS No.: 376608-74-1
Target:  

Drug Intermediate

Research Areas:  

Others

2-(((3aR,4S,6R,6aS)-6-((5-Amino-6-chloro-2-(propylthio)pyrimidin-4-yl)amino)-2,2-dimethyltetrahydro-3aH-cyclopenta[d][1,3]dioxol-4-yl)oxy)ethanol is a drug intermediate for synthesis of various active compounds.
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Cat. No.: HY-N0305R
CAS No.: 5451-09-2
Synonyms: 5-ALA hydrochloride (Standard); δ-Aminolevulinic acid hydrochloride (Standard); 5-Amino-4-oxopentanoic acid hydrochloride (Standard)
5-Aminolevulinic acid (hydrochloride) (Standard) is the analytical standard of 5-Aminolevulinic acid (hydrochloride). This product is intended for research and analytical applications. 0
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Cat. No.: HY-140194
CAS No.: 1446282-18-3
Purity:  ≥98.0%
Target:  

PROTAC Linkers

Research Areas:  

Cancer

Amino-PEG5-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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Cat. No.: HY-77822
CAS No.: 320-51-4
5-Amino-2-chlorobenzotrifluoride is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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Cat. No.: HY-W001994
CAS No.: 6628-77-9
5-Amino-2-methoxypyridine is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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Cat. No.: HY-W011983
CAS No.: 61348-28-5
Research Areas:  

Others

5-Amino-2-((tert-butoxycarbonyl)amino)-5-oxopentanoic acid is a glutamine derivative .
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