6 Results for "

8-pCPT-2'-O-Me-cAMP-AM

" in MedChemExpress (MCE) Product Catalog:
Products (6)

6 Results for "8-pCPT-2'-O-Me-cAMP-AM" in MCE Product Catalog:

Cat. No.: HY-107544
CAS No.: 1152197-23-3
Target:  

PKA

Research Areas:  

Metabolic Disease

8-pCPT-2'-O-Me-cAMP-AM is a cyclic AMP analogue, selectively activates Epac-Rap signaling pathway. 8-pCPT-2'-O-Me-cAMP-AM protects renal function by activating Epac from ischemia injury. 8-pCPT-2'-O-Me-cAMP-AM also stimulates insulin secretion by interaction with PKA pathway .
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1 Cited Publications
Cat. No.: HY-107543
CAS No.: 634207-53-7
Purity:  99.81%
Synonyms: 8-CPT-2'-O-Me-cAMP sodium
Target:  

Ras

Research Areas:  

Cardiovascular Disease

8-pCPT-2′-O-Me-cAMP (8-CPT-2'-O-Me-cAMP) sodium, an analog of cAMP, is an activator of exchange proteins activated by cAMP (Epac). 8-pCPT-2′-O-Me-cAMP sodium activates Epac1 (EC50 = 2.2 μM), but not PKA (EC50 >10 μM). 8-pCPT-2′-O-Me-cAMP sodium stimulates Epac-mediated Ca 2+ release in pancreatic β-cells in vitro. 8-pCPT-2′-O-Me-cAMP sodium is a Rap1 activator. 8-pCPT-2′-O-Me-cAMP sodium enhances the retinal pigment epithelium barrier against the pathological choroidal endothelial cell invasion that occurs in macular degeneration .
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Cat. No.: HY-116312
CAS No.: 510774-50-2
Synonyms: 8-CPT-2'-O-Me-cAMP
Target:  

Ras

Research Areas:  

Cardiovascular Disease

8-pCPT-2′-O-Me-cAMP (8-CPT-2'-O-Me-cAMP), an analog of cAMP, is an activator of exchange proteins activated by cAMP (Epac). 8-pCPT-2′-O-Me-cAMP activates Epac1 (EC50 = 2.2 μM), but not PKA (EC50 >10 μM). 8-pCPT-2′-O-Me-cAMP stimulates Epac-mediated Ca 2+ release in pancreatic β-cells in vitro. 8-pCPT-2′-O-Me-cAMP is a Rap1 activator. 8-pCPT-2′-O-Me-cAMP enhances the retinal pigment epithelium barrier against the pathological choroidal endothelial cell invasion that occurs in macular degeneration .
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Cat. No.: HY-107543R
CAS No.: 634207-53-7
Synonyms: 8-CPT-2'-O-Me-cAMP sodium (Standard)
Target:  

Reference Standards Ras

Research Areas:  

Cardiovascular Disease

8-pCPT-2′-O-Me-cAMP sodium (Standard) is the analytical standard of 8-pCPT-2′-O-Me-cAMP (sodium) (HY-107543). This product is intended for research and analytical applications. 8-pCPT-2′-O-Me-cAMP (8-CPT-2'-O-Me-cAMP) sodium, an analog of cAMP, is an activator of exchange proteins activated by cAMP (Epac). 8-pCPT-2′-O-Me-cAMP sodium activates Epac1 (EC50 = 2.2 μM), but not PKA (EC50 >10 μM). 8-pCPT-2′-O-Me-cAMP sodium stimulates Epac-mediated Ca2+ release in pancreatic β-cells in vitro. 8-pCPT-2′-O-Me-cAMP sodium is a Rap1 activator. 8-pCPT-2′-O-Me-cAMP sodium enhances the retinal pigment epithelium barrier against the pathological choroidal endothelial cell invasion that occurs in macular degeneration .
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Cat. No.: HY-137630
CAS No.: 634208-37-0
Target:  

Ras

Research Areas:  

Metabolic Disease

Sp-8-pCPT-2'-O-Me-cAMPS is an activator of EPAC. Sp-8-pCPT-2'-O-Me-cAMPS can be used in endocrine metabolism related research .
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Cat. No.: HY-134332
CAS No.: 78710-84-6
Synonyms: 8-(4-Chlorophenylthio)-5'-AMP
Target:  

PKA PKG

Research Areas:  

Others

8-pCPT-5'-AMP is an analogue of 5'-AMP and a lipophilic activator of PKA, PKG and Epac (exchange protein activated by cAMP) .
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