2 Results for "

Amyloid-β-IN-2

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "Amyloid-β-IN-2" in MCE Product Catalog:

Cat. No.: HY-171348
CAS No.: 1603833-55-1
Target:  

Amyloid-β γ-secretase

Research Areas:  

Neurological Disease

Amyloid-β-IN-2 (Compound EX.112) is a selective γ-secretase inhibitor. Amyloid-β-IN-2 inhibits Aβ42 secretion in H4 cells with an EC50 value of 226 nM. Amyloid-β-IN-2 is promising for research of Alzheimer's disease (AD) and other diseases related to Aβ deposition .
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1
1 Cited Publications
Cat. No.: HY-P99216
CAS No.: 1178862-65-1
Synonyms: PF-04360365; RN 1219

Target:  

Amyloid-β

Research Areas:  

Neurological Disease

Ponezumab (PF-04360365; RN 1219) is a humanized anti-amyloid(Amyloid-β) IgG2 monoclonal antibody. Ponezumab reduces levels in the central nervous system and improves the performance of mice in various learning and memory models. Ponezumab is applicable to the research of Alzheimer's disease .
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