2. JAK/STAT Signaling Protein Tyrosine Kinase/RTK
  3. EGFR
  4. Ponezumab

Ponezumab  (Synonyms: PF-04360365; RN 1219)

Cat. No.: HY-P99216 Purity: 95.00%
COA

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Ponezumab (PF-04360365) is a humanised anti-amyloid IgG2 monoclonal antibody. Ponezumab reduces Aβ levels in the central nervous system and improves performance in mice in various models of learning and memory. Ponezumab can be used in study of Alzheimer's disease.

For research use only. We do not sell to patients.

Ponezumab Chemical Structure

Ponezumab Chemical Structure

CAS No. : 1178862-65-1

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Based on 1 publication(s) in Google Scholar

Ponezumab Related Antibodies

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Description

Ponezumab (PF-04360365) is a humanised anti-amyloid IgG2 monoclonal antibody. Ponezumab reduces Aβ levels in the central nervous system and improves performance in mice in various models of learning and memory. Ponezumab can be used in study of Alzheimer's disease[1].

IC50 & Target

IgG2[1].
Clinical Trial
CAS No.
Appearance

Liquid

Color

Colorless to light yellow

SMILES

[Ponezumab]
Shipping

Shipping with dry ice.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation

Purity: 95.00%

COA (231 KB)

Handling Instructions (2659 KB)
References
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Ponezumab Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Ponezumab1178862-65-1PF-04360365 RN 1219PF04360365PF 04360365RN1219RN 1219RN-1219EGFREpidermal growth factor receptorErbB-1HER1Aβalzheimer's diseaseInhibitorinhibitorinhibit

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