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Ponezumab

(Synonyms: PF-04360365; RN 1219)
1 Cited Publications
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Based on 1 publication(s) in Google Scholar

Ponezumab (PF-04360365; RN 1219) is a humanized anti-amyloid-β (Amyloid-β) IgG2 monoclonal antibody. Ponezumab reduces Aβ levels in the central nervous system and improves the performance of mice in various learning and memory models. Ponezumab is applicable to the research of Alzheimer's disease.

For research use only. We do not sell to patients.

  • Purity: 97.89%
  • CAS No.: 1178862-65-1
  • Molecular Weight:145.65 kDa
  • Storage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Experimental Validation Results for Ponezumab
  • Experimental Validation Results for Ponezumab
  • Ponezumab Chemical Structure
    Ponezumab Chemical Structure
CAS No.: 1178862-65-1
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Assay Types
  • 1/16

    Human IgG2 kappa

  • 1/16

    Flow cytometric analysis of 1.5×106 HUVEC cells with Ponezumab (HY-P99216, red). Cells were fixed with 4% paraformaldehyde and permeabilised with 90% methanol. Then stained with the primary antibody at 1/200 dilution for an hour at 4℃. Goat Anti-Human IgG H&L (AF488) (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG1 kappa, Isotype Control (HY-P99001, blue) was used as the isotype control).

  • Ponezumab Chemical Structure
    1/16
  • Ponezumab
  • Flow cytometric analysis of 1.5×106 HUVEC cells with Ponezumab (HY-P99216, red). Cells were fixed with 4% paraformaldehyde and permeabilised with 90% methanol. Then stained with the primary antibody at 1/200 dilution for an hour at 4℃. Goat Anti-Human IgG H&L (AF488) (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG1 kappa, Isotype Control (HY-P99001, blue) was used as the isotype control).