6 Results for "

Andrographis paniculata NEES

" in MedChemExpress (MCE) Product Catalog:
Products (6)

6 Results for "Andrographis paniculata NEES" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-N0677
CAS No.: 786593-06-4
Dehydroandrographolide succinate can be extracted from herbal medicine Andrographis paniculata (Burm f) Nees, is widely used in research for viral pneumonia and viral upper respiratory tract infections because of its immunostimulatory, anti-infective and anti-inflammatory effect. Dehydroandrographolide succinate exerts antithrombotic effect. Dehydroandrographolide succinate significantly inhibits the platelet aggregation rate (ED50 = 386.9 mg/kg) by decreasing TXB2 levels. Dehydroandrographolide succinate mitigates muscle astrophy via the Akt/GSK3β and MuRF-1 pathways .
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-N0857
CAS No.: 79233-15-1
Deoxyandrographolide is an orally active lactone found in the Andrographis paniculata Nees. Deoxyandrographolide shows a KD of 38.4 μM of HDAC1. Deoxyandrographolide enhances GLUT4 plasma membrane translocation, activates PI3K and AMPK-dependent signaling pathways, suppresses fasting blood glucose, serum insulin, triglycerides, and LDL-cholesterol levels. Deoxyandrographolide enhances HDAC1 expression via inhibited ubiquitination degradation, represses H3K4me3, improves chromosome stability, and restrains aging biomarkers p16, p21, γH2A.X, p53 and ROS production. Deoxyandrographolide interacts with Foot-and-Mouth Disease Virus 3Cpro active site, inhibits protease and IFN-antagonist activity, derepresses ISG expression, and inhibits viral replication. Deoxyandrographolide can be used for the researches of type 2 diabetes mellitus, vascular senescence and virus infection .
loading...
    loading...
Cat. No.: HY-N1492
CAS No.: 219721-33-2
Target:  

Others

Domaines de recherche:  

Others

14-Deoxy-12-hydroxyandrographolide is a labdane type diterpene compound isolated from the leaves of Andrographis paniculata Nees .
loading...
    loading...
Cat. No.: HY-N2867
CAS No.: 82209-76-5
Andrographiside is a labdane diterpenoid glucoside that can be isolated from the leaves of Andrographis paniculata Nees. Andrographiside has antihepatotoxic and antioxidative effects. Andrographiside shows protective effects on mice with hepatotoxicity induced by carbon tetrachloride or tert-butylhydroperoxide (tBHP) . Andrographiside is a novel biofilm inhibitor of Pseudomonas aeruginosa PAO1 by modulating quorum-sensing proteins .
loading...
    loading...
Cat. No.: HY-N18352
CAS No.: 21681-03-8
8-Methylandrograpanin (Compound I) is a diterpene found in the leaves of Andrographis paniculata (Burm.f.) Nees .
loading...
    loading...
Cat. No.: HY-N20643
CAS No.: 160495-64-7
(1R,4aS,5R,6R,8aS)-14-Deoxy-12-hydroxyandrographolide is an ent-kaurane-type diterpenoid. (1R,4aS,5R,6R,8aS)-14-Deoxy-12-hydroxyandrographolide induces leukemia cell differentiation by enhancing phagocytosis and inhibits leukemia cell growth. (1R,4aS,5R,6R,8aS)-14-Deoxy-12-hydroxyandrographolide can be used in the research of murine myeloid leukemia .
loading...
    loading...