17 Results for "

Anti-CD19 antibody

" in MedChemExpress (MCE) Product Catalog:
Products (17)

17 Results for "Anti-CD19 antibody" in MCE Product Catalog:

Cat. No.: HY-P990349

Target:  

CD19

Research Areas:  

Inflammation/Immunology

The Anti-CD19 Antibody is a humanized antibody expressed in CHO cells, targeting CD19. The Anti-CD19 Antibody contains a huIgG1 heavy chain and a huκ light chain, with a predicted molecular weight (MW) of 145 kDa. The isotype control for Anti-CD19 Antibody can be referenced as Human IgG1 kappa, Isotype Control (HY-P99001).
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2 Cited Publications
Cat. No.: HY-P99711
CAS No.: 1875032-68-0
Synonyms: RB4v1.2

Target:  

CD19 ADC Antibodies

Research Areas:  

Cancer

Loncastuximab (RB4v1.2) is an anti-CD19 monoclonal antibody. Loncastuximab has antitumor activity and can be used in the research of Non-Hodgkin Lymphoma (NHL) and Diffuse Large B-cell Lymphoma (DLBCL). Loncastuximab is capable of synthesizing the ADC molecule Loncastuximab tesirine (HY-P99349) .
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1 Cited Publications
Cat. No.: HY-P99113
CAS No.: 1299440-37-1
Synonyms: MEDI-551
Inebilizumab is an anti-CD19 monoclonal antibody (mAb) with enhanced antibody-dependent cell-mediated cytotoxicity against B cells. Inebilizumab can be used for multiple sclerosis and neuromyelitis optica research .
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1 Cited Publications
Cat. No.: HY-P99285
CAS No.: 1630074-14-4
Synonyms: hBU 12

Target:  

ADC Antibodies CD19

Research Areas:  

Cancer

Denintuzumab (hBU 12) is a recombinant humanized anti-CD19 monoclonal antibody. Denintuzumab binds to CD19 on the surface of B cells. Denintuzumab can be used as the antibody moiety (ADC antibody) of antibody-drug conjugates to synthesize ADC, Denintuzumab Mafodotin (SGN-CD19A). Denintuzumab Mafodotin can be used in the research of acute lymphoblastic leukemia .
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Cat. No.: HY-P991028
CAS No.: 2892667-02-4
Synonyms: AZD0486; TNB-486

Research Areas:  

Cancer

Surovatamig (AZD0486; TNB-486) is a fully human anti-CD19/CD3 IgG4 bispecific antibody. Surovatamig triggers T cell activation, releases cytotoxic granules, and induces T cell-dependent cellular cytotoxicity and tumor cell lysis. Surovatamig can reduces release of pro-inflammatory cytokines including IL-2, IFNγ, TNF. Surovatamig can be used for the research of cancer, such as B cell non-Hodgkin lymphoma .
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Cat. No.: HY-P99761
CAS No.: 1690307-05-1
Synonyms: XmAb5871

Target:  

CD19 Apoptosis

Research Areas:  

Inflammation/Immunology

Obexelimab (XmAb5871) is a humanized anti-CD19 antibody. Obexelimab works by inhibiting B cell receptor (BCR) mediated calcium influx and promoting the phosphorylation of Fc γ receptor IIb (FcγRIIb), which reduces B cell activation and function, leading to B cell apoptosis. Obexelimab can be used in research for rheumatoid arthritis and systemic lupus erythematosus .
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Cat. No.: HY-P99113A

Target:  

CD19

Inebilizumab (FUT8-KO) is an anti-CD19 monoclonal antibody expressed by CHO cells with the fucosyltransferase 8 gene (FUT8) knocked out. Fucose deficiency enhances the antibody-dependent cellular cytotoxicity (ADCC) effect of the antibody.Inebilizumab (FUT8-KO) exhibits enhanced ADCC against B cells and can be used for research on multiple sclerosis and neuromyelitis optica .
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Cat. No.: HY-P990870

Research Areas:  

Inflammation/Immunology

Anti-CD19 Antibody (4G7) is an anti-human CD19 IgG1 monoclonal antibody. Anti-CD19 Antibody (4G7) reduces the killing effect of CAR T cells on Raji cells. Anti-CD19 Antibody (4G7) can be used for research on immunology. Anti-CD19 Antibody (4G7) is often used in flow cytometry. The recommend isotype control of Anti-CD19 Antibody (4G7): Mouse IgG1 kappa, Isotype Control (HY-P99977) .
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Cat. No.: HY-P990729
CAS No.: 2720478-38-4
Synonyms: VB-119

Target:  

CD19

Research Areas:  

Inflammation/Immunology

Budoprutug is an anti-CD19 human IgG1 κ monoclonal antibody . Recommend Isotype Controls: Human IgG1 kappa, Isotype Control (HY-P99001).
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Cat. No.: HY-P990694
CAS No.: 2607644-43-7
Synonyms: TG-1801

Target:  

CD19 CD47

Research Areas:  

Inflammation/Immunology

Zeripatamig is an anti-CD19/CD47 human IgG1 κ monoclonal antibody . Recommend Isotype Controls: Human IgG1 kappa, Isotype Control (HY-P99001).
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Cat. No.: HY-P99577
CAS No.: 235428-87-2

Target:  

CD19

Research Areas:  

Cancer

Taplitumomab is an anti-CD19 monoclonal antibody. Taplitumomab paptox can be used in cancer research.
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Cat. No.: HY-P991839

Target:  

CD19

Research Areas:  

Cancer

Anti-CD19 Antibody (FMC63) is an antibody that binds to CD19, with a human Kd value ranging from 0.42 nM to 149 nM. Anti-CD19 Antibody (FMC63) mediates tumor cell killing, cytokine secretion, stable CAR expression, T cell activation and memory differentiation. Anti-CD19 Antibody (FMC63) fails to eliminate lymphoma cells carrying CD19 point mutations or co-expressing FMC63-CAR19, induces higher levels of activation-induced cell death, and reduces cell persistence. Anti-CD19 Antibody (FMC63) can be used in research related to B-cell non-Hodgkin's lymphoma, B-cell acute lymphoblastic leukemia, relapsed or refractory diffuse large B-cell lymphoma, etc .
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Cat. No.: HY-P991897

Target:  

CD19

Research Areas:  

Cancer

Anti-CD19 Antibody (hA19) is an antibody against human CD19. Recommend Isotype Controls:?Human IgG1 kappa, Isotype Control (HY-P99001).
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Cat. No.: HY-P991542
CAS No.: 1931954-95-8

Target:  

CD19

Research Areas:  

Cancer

GBR-401 is a humanized anti-CD19 monoclonal antibody with high affinity for FcγRIIIa. GBR-401 exerts a potent in vitro and in vivo cytotoxic activity against various B-cell malignancies. GBR-401 induces cell death by antibody dependent cellular cytotoxicity (ADCC) and direct killing effect. GBR-401 demonstrates potent activity of depleting malignant B cells and prolongs mice survival in multiple xenograft severe combined immunodeficiency (SCID) mice models .
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Cat. No.: HY-P991231

Target:  

CD19

Research Areas:  

Cancer

DI-B4 is an anti-CD19 monoclonal antibody that can bind to CD19 on the surface of B cells and has anti-tumor activity .
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Cat. No.: HY-P991900

Target:  

CD19

Research Areas:  

Inflammation/Immunology

LY3541860 is a selective anti-CD19 antibody that both binds human CD19 with high affinity and selectively binds human B cells (Kd values: 76.8 pM and 94.5 nM for humans and cynomolgus monkeys, respectively). LY3541860 inhibits CpG-induced CD69 expression (IC50 = 0.006 nM). LY3541860 exhibits potent B cell inhibitory activities. LY3541860 can inhibit both BCR- and TLR-induced human B cell activation. LY3541860 can be used for the research of autoimmune diseases .
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Cat. No.: HY-P991898
Synonyms: RD126

Target:  

CD19

Research Areas:  

Inflammation/Immunology

IASO-782 (RD126) is a fully human monoclonal antibody targeting human CD19. The Fc segment of IASO-782 is mutated to enhance antibody-dependent cell-mediated cytotoxicity (ADCC) while maintaining the integrity of other Fc segment functions, such as ADCP. IASO-782 effectively eliminates CD19+ B cells, plasmablasts, and some plasma cells, thereby reducing or completely eliminating autoreactive antibodies produced by these cells. IASO-782 can be used for the study of immune thrombocytopenic purpura (ITP), warm autoimmune hemolytic anemia (wAIHA) and systemic lupus erythematosus (SLE).
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