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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
6 Results for "
Anti-proliferation A549 cells
" in MedChemExpress (MCE) Product Catalog:
Products (6)
6 Results for "Anti-proliferation A549 cells" in MCE Product Catalog:
Cat. No.: HY-178106
Target:
Research Areas:
SCN2 is a esterase-responsive prodrug-based amphiphile composed of SN38 (HY-13704) and di-(triazole-[12]aneN3, N) moiety through a 7‑carbon alkyl chains. SCN2 has excellent self-assembly and reversible siRNA condensation capabilities as well as anti-proliferation activity against cancer cells. SCN2 can be used for synthesis of nanoparticles for drug delivery of lung cancer .
Cat. No.: HY-152468
CAS No.: 3038789-74-8
Antitumor agent-83 is an activator of pro-apoptotic protein BAX and has significant anti-proliferation effect on tumor cells. Antiumor agent-83 mediates cell Apoptosis by inducing the conformational activation of BAX and has inhibitory effect on A549 cell cycle. Antiumor agent-83 has good metabolic stability and CYPs spectrum in vitro .
Cat. No.: HY-N12617
Category:
Cat. No.: HY-168251
CAS No.: 2933125-05-2
Research Areas:
PROTAC BRM/BRG1 degrader-3 is a BRM/BRG1 PROTAC degrader, exhibiting a DC50 of less than 1 nM for BRM degradation and a DC50 of greater than 1 nM for BRG1 degradation in SW1573 cells. PROTAC BRM/BRG1 degrader-3 shows moderate inhibitory activity against CYP2D6 and hERG. PROTAC BRM/BRG1 degrader-3 inhibits cancer cell proliferation and tumor tissue growth, and exhibits favorable metabolic stability in liver microsomes. PROTAC BRM/BRG1 degrader-3 can be used in non-small cell lung cancer-related research .
Cat. No.: HY-177224
CAS No.: 577747-87-6
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Research Areas:
Antitumor agent-205 (compound 9), an Ecteinascidin derivative, is an antitumor agent. Antitumor agent-205 exhibits anti-proliferation activity against A549 and HT29 cells , with GI50 values of 16.4 nM for each cell line. Antitumor agent-205 can be used for lung and colon cancer research .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
