2. Apoptosis
  3. Apoptosis
  4. Antiproliferative agent-19

Antiproliferative agent-19 (compound 4a) is an anti-cancer agent that exerts anti-proliferative effects on lung cancer cells by inducing apoptosis. antiproliferative agent-19 also induces cell cycle arrest in the G2/M phase.

For research use only. We do not sell to patients.

Antiproliferative agent-19 Chemical Structure

Antiproliferative agent-19 Chemical Structure

Size Stock
50 mg   Get quote  
100 mg   Get quote  
250 mg   Get quote  
Synthetic products have potential research and development risk.

* Please select Quantity before adding items.

This product is a controlled substance and not for sale in your territory.

Antiproliferative agent-19 Related Antibodies

Top Publications Citing Use of Products

  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

Antiproliferative agent-19 (compound 4a) is an anti-cancer agent that exerts anti-proliferative effects on lung cancer cells by inducing apoptosis. antiproliferative agent-19 also induces cell cycle arrest in the G2/M phase[1].

In Vitro

Antiproliferative agent-19 (0-50 µM; 72 h) significantly inhibits the viability of human nonsmall cell lung cancer and colon cancer cells[1].
Antiproliferative agent-19 (11.33 µM; 24, 48, and 72 h) induces sub‑G1‑phase cell cycle arrest in A549 cells[1].
Antiproliferative agent-19 (11.33 µM; 6, 24 and 48 h) induces apoptosis via intrinsic and extrinsic pathways in A549 cells[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Antiproliferative agent-19 Related Antibodies

Cell Cytotoxicity Assay[1]

Cell Line: HCT-116 and A549 cells
Concentration: 0-50 µM
Incubation Time: 72 h
Result: Inhibited the growth of HCT-116 and A549 cells with IC50 values of 12.18 and 11.33 µM, respectively.

Cell Cycle Analysis[1]

Cell Line: A549 cells
Concentration: 11.33 µM
Incubation Time: 24, 48, and 72 h
Result: Increased cells of G2 phase significantly from 3.2% (DMSO-treated cells) to 15.5% and 33.8% (cells treated with the compound for 24 and 48 h, respectively).

Apoptosis Analysis[1]

Cell Line: A549 cells
Concentration: 11.33 µM
Incubation Time: 6, 24 and 48 h
Result: Induced caspase-dependent cell death.
Molecular Weight

365.47

Formula

C26H23NO
SMILES

O=C1NC2=C(CCCC2)C(C3=CC=CC=C3)=C1CC4=C5C=CC=CC5=CC=C4
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
  • No file chosen (Maximum size is: 1024 Kb)
  • If you have published this work, please enter the PubMed ID.
  • Your name will appear on the site.

Antiproliferative agent-19 Related Classifications

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Antiproliferative agent-19Antiproliferative agent19Antiproliferative agent 19Apoptosisanti-proliferationapoptosiscell cycle arrestcancerG2/MHCT-116 cellA549 cellInhibitorinhibitorinhibit

Your Recently Viewed Products:

Inquiry Online

Your information is safe with us. * Required Fields.

Product Name

  

Salutation

Applicant Name *

 

Email Address *

Phone Number *

 

Organization Name *

Department *

 

Requested quantity *

Country or Region *

      

Remarks

Bulk Inquiry

Inquiry Information

Product Name:
Antiproliferative agent-19
Cat. No.:
HY-152099
Quantity:
MCE Japan Authorized Agent:

Customer Review

Thank You for Your Feedback!

Request for HNMR Report

Please fill out this form to request the QC report. We will send it to your Email address shortly.

Your information is safe with us. * Required Fields.

Product Name

  

Lot #

Applicant Name *

 

Email Address *

Phone Number

 

Department *

Organization Name *

 

Country or Region *

Remarks

Request for HNMR Report

We have received your request and will respond to you as soon as possible.