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Pathways Recommended: Apoptosis
Results for "

Apoptosis induction

" in MedChemExpress (MCE) Product Catalog:

1078

Inhibitors & Agonists

2

Peptides

4

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35

Natural
Products

19

Isotope-Labeled Compounds

70

Click Chemistry

877

Oligonucleotides

Targets Recommended:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-13735A
    Quinacrine dihydrochloride
    5+ Cited Publications

    Mepacrine dihydrochloride; SN-390 dihydrochloride

    Parasite Apoptosis Autophagy Mitophagy Infection Cancer
    Quinacrine (Mepacrine) dihydrochloride is an orally bioavailable antimalarial agent, which possess anticancer effect both in vitro and vivo. Quinacrine dihydrochloride suppresses NF-κB and activate p53 signaling, which results in the induction of the apoptosis .
    Quinacrine dihydrochloride
  • HY-108431
    MN58b
    1 Publications Verification

    Apoptosis Cancer
    MN58b is a selective choline kinase α (CHKα) inhibitor, and results in inhibition of phosphocholine synthesis. MN58b reduces cell growth through the induction of apoptosis, and also has antitumoral activity .
    MN58b
  • HY-15323
    PRT062607 Hydrochloride
    4 Publications Verification

    P505-15 Hydrochloride

    Syk Mixed Lineage Kinase PAK Pyk2 FAK Apoptosis Src Cancer
    PRT062607 (P505-15) Hydrochloride is an orally available Syk inhibitor (IC50: 1 nM) that inhibits inflammation and induction Apoptosis. PRT062607 Hydrochloride exerts potent antitumor activity in tumor xenograft mouse models .
    PRT062607 Hydrochloride
  • HY-W015084
    β-Ionone
    1 Publications Verification

    Environmental Pollutants Apoptosis Cancer
    β-Ionone is effective in the induction of apoptosis in gastric adenocarcinoma SGC7901 cells. Anti-cancer activity .
    β-Ionone
  • HY-12960

    FLT3-​IN-​1

    FLT3 c-Kit Apoptosis Cancer
    SKLB4771 is a potent and selective Flt3 inhibitor with an IC50 value of 10 nM. SKLB4771 downregulates the phosphorylation of FLT3/STAT5/ERK, blocks cell proliferation, and induces apoptosis in tumor tissue .
    SKLB4771
  • HY-N0438
    Pimpinellin
    1 Publications Verification

    Apoptosis Cancer
    Pimpinellin is a constituent of Cyrtomium fortumei (J.). Pimpinellin inhibits the growth of tumor cells via the induction of tumor cell apoptosis .
    Pimpinellin
  • HY-13735B

    Mepacrine hydrochloride hydrate; SN-390 hydrochloride hydrate

    Parasite Apoptosis Autophagy Mitophagy Infection Cancer
    Quinacrine hydrochloride hydrate (Mepacrine hydrochloride hydrate) is an antimalarial agent, which possess anticancer effect both in vitro and vivo. Quinacrine hydrochloride hydrate suppresses NF-κB and activates p53 signaling, which results in the induction of the apoptosis .
    Quinacrine hydrochloride hydrate
  • HY-N1925
    Tea polyphenol
    2 Publications Verification

    Apoptosis Autophagy Neurological Disease Inflammation/Immunology Cancer
    Tea polyphenol is the floorboard of phenolic compounds in tea. Tea polyphenol exhibits biological activity including antioxidant and anti-cancer activities, inhibition of cell proliferation, induction of apoptosis, cell cycle arrest and modulation of carcinogen metabolism .
    Tea polyphenol
  • HY-176954

    Proton Pump Ras Autophagy Apoptosis Cancer
    RSC-1255 is a potent and selective Vacuolar H⁺-ATPase (V-ATPase) inhibitor that directly binds the mammalian V-ATPase complex with a Kd = 23 nM. RSC-1255 exhibits preferential cytotoxicity toward KRAS-mutant cancer cells, especially KRAS G13D and KRAS G12V cells. RSC-1255 induces apoptosis and blocks lysosomal acidification, autophagy, and macropinocytosis in cancer cells. RSC-1255 can be used for the study of KRAS-driven lung and colon cancers .
    RSC-1255
  • HY-103694

    Nucleoside Antimetabolite/Analog Others
    Nebularine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
    Nebularine
  • HY-137977
    DMU-212
    2 Publications Verification

    ERK Apoptosis Cancer
    DMU-212 is a methylated derivative of Resveratrol (HY-16561), with antimitotic, anti-proliferative, antioxidant and apoptosis promoting activities. DMU-212 induces mitotic arrest via induction of apoptosis and activation of ERK1/2 protein. DMU-212 has orally active .
    DMU-212
  • HY-W009163
    5-Bromouridine
    2 Publications Verification

    Nucleoside Antimetabolite/Analog Cancer
    5-Bromouridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
    5-Bromouridine
  • HY-W244398

    Nucleoside Antimetabolite/Analog Cancer
    2-Thiocytidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
    2-Thiocytidine
  • HY-W587829

    Nucleoside Antimetabolite/Analog Cancer
    4-Thiothymidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
    4-Thiothymidine
  • HY-112581

    Nucleoside Antimetabolite/Analog Cancer
    5-Methoxyuridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
    5-Methoxyuridine
  • HY-13603
    Crolibulin
    1 Publications Verification

    EPC2407

    Microtubule/Tubulin Apoptosis Cardiovascular Disease Cancer
    Crolibulin (EPC2407) is a tubulin polymerization inhibitor, with potent apoptosis induction and cell growth inhibition. Crolibulin has anti-tumor activity. Crolibulin also has cardiovascular toxicity and neurotoxicity .
    Crolibulin
  • HY-131795
    2-Methylthioadenosine
    1 Publications Verification

    Nucleoside Antimetabolite/Analog Cancer
    2-Methylthioadenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
    2-Methylthioadenosine
  • HY-130805

    OHUrd

    Nucleoside Antimetabolite/Analog Others Cancer
    5-Hydroxyuridine (OHUrd) is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
    5-Hydroxyuridine
  • HY-W154568

    6-MPR

    Nucleoside Antimetabolite/Analog Others Cancer
    6-Methylpurine riboside is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
    6-Methylpurine riboside
  • HY-122496

    Syringidin

    Apoptosis Cancer
    Malvidin (chloride) is a bioactive compound isolated from grape. Malvidin shows cytotoxicity through the arrest of the G2/M phase of cell cycle and induction of apoptosis. Malvidin can be used for the research of cancer .
    Malvidin chloride
  • HY-154534

    Nucleoside Antimetabolite/Analog Cancer
    Alpha-Adenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
    Alpha-Adenosine
  • HY-151414

    Nucleoside Antimetabolite/Analog Cancer
    3'-Deoxyinosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
    3'-Deoxyinosine
  • HY-W014306

    Nucleoside Antimetabolite/Analog Cancer
    2',3'-Dideoxyuridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
    2',3'-Dideoxyuridine
  • HY-130806

    H2dUrd

    Nucleoside Antimetabolite/Analog Cancer
    Dihydrodeoxyuridine (H2dUrd) is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
    Dihydrodeoxyuridine
  • HY-168926

    Reactive Oxygen Species (ROS) Apoptosis Cancer
    NQO2-IN-1 (Compound 20b) is the inhibitor for quinone oxidoreductase (NQO) that inhibits NQO2 with an IC50 of 95 nM. NQO2-IN-1 overcomes the resistance of NSCLC cells to tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) by induction of ROS and apoptosis .
    NQO2-IN-1
  • HY-15324
    PRT062607 acetate
    4 Publications Verification

    P505-15 acetate; PRT-2607 acetate; BIIB-057 acetate

    Syk Src Mixed Lineage Kinase PAK Pyk2 FAK Apoptosis Cancer
    PRT062607 (P505-15) acetate is an orally available Syk inhibitor (IC50: 1 nM) that inhibits inflammation and induction Apoptosis. PRT062607 acetate exerts potent antitumor activity in tumor xenograft mouse models . .
    PRT062607 acetate
  • HY-W013259

    Nucleoside Antimetabolite/Analog Cancer
    6-Methylmercaptopurine riboside is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
    6-Methylmercaptopurine riboside
  • HY-154530

    Nucleoside Antimetabolite/Analog Cancer
    DMTr-TNA-C(Bz)-amidite is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
    DMTr-TNA-C(Bz)-amidite
  • HY-152682

    Nucleoside Antimetabolite/Analog Others Cancer
    5-Ethyluridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
    5-Ethyluridine
  • HY-134294

    Nucleoside Antimetabolite/Analog Others
    8-Chloroguanosine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
    8-Chloroguanosine
  • HY-152617

    Nucleoside Antimetabolite/Analog Cancer
    4’-Thioinosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
    4’-Thioinosine
  • HY-152368

    Nucleoside Antimetabolite/Analog Others
    8-Hydrazinoadenosine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
    8-Hydrazinoadenosine
  • HY-152544

    Nucleoside Antimetabolite/Analog Cancer
    8-Allylthioguanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
    8-Allylthioguanosine
  • HY-W609639

    Nucleoside Antimetabolite/Analog Cancer
    2’-Deoxyisocytidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
    2’-Deoxyisocytidine
  • HY-154329

    Nucleoside Antimetabolite/Analog Cancer
    2-Deoxyuridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
    2-Deoxyuridine
  • HY-114372

    Lipoxygenase Caspase Apoptosis Cancer
    Lycopodine, a pharmacologically important bioactive component derived from Lycopodium clavatumspores, triggers apoptosis by modulating 5-lipoxygenase, and depolarizing mitochondrial membrane potential in refractory prostate cancer cells without modulating p53 activity . Lycopodine inhibits proliferation of HeLa cells through induction of apoptosis via caspase-3 activation .
    Lycopodine
  • HY-152510

    Nucleoside Antimetabolite/Analog Cancer
    5-(Aminomethyl)uridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
    5-(Aminomethyl)uridine
  • HY-105006

    2-Methoxyadenosine; 2-O-Methylisoguanosine

    Nucleoside Antimetabolite/Analog Cancer
    Spongosine (2-Methoxyadenosine) is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
    Spongosine
  • HY-152586

    Nucleoside Antimetabolite/Analog Others
    2′,3′-Anhydroadenosine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
    2′,3′-Anhydroadenosine
  • HY-152794

    Nucleoside Antimetabolite/Analog Others
    7-Methyl wyosine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
    7-Methyl wyosine
  • HY-W108399

    Nucleoside Antimetabolite/Analog Cancer
    3’-O-t-Bulyldimethylsilylthymidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
    3’-O-t-Bulyldimethylsilylthymidine
  • HY-152318

    Nucleoside Antimetabolite/Analog Others
    Adenosine-2-carboxamide is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
    Adenosine-2-carboxamide
  • HY-154537

    Nucleoside Antimetabolite/Analog Cancer
    3’-O-Methyl inosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
    3’-O-Methyl inosine
  • HY-154616

    Nucleoside Antimetabolite/Analog Cancer
    2’-O-Phthalimidopropyl uridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
    2’-O-Phthalimidopropyl uridine
  • HY-W022290

    Nucleoside Antimetabolite/Analog Cancer
    5-Bromocytidine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
    5-Bromocytidine
  • HY-152654

    Nucleoside Antimetabolite/Analog Others
    4′-Thiocytidine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
    4′-Thiocytidine
  • HY-154242

    Nucleoside Antimetabolite/Analog Cancer
    8-Methylguanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
    8-Methylguanosine
  • HY-152807

    Nucleoside Antimetabolite/Analog Others
    4’-Thioadenosine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
    4’-Thioadenosine
  • HY-152321

    Nucleoside Antimetabolite/Analog Cancer
    5-Hydroxy-arabinouridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
    5-Hydroxy-arabinouridine
  • HY-147822

    Apoptosis Cancer
    Apoptosis inducer 6 (compound 4e) is an anticancer agent with a broad-spectrum anticancer activity. Apoptosis inducer 6 triggers cell death through the induction of apoptosis .
    Apoptosis inducer 6

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