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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
6 Results for "
Aspartate aminotransferase, Human
" in MedChemExpress (MCE) Product Catalog:
Products (6)
6 Results for "Aspartate aminotransferase, Human" in MCE Product Catalog:
Research Areas:
Aspartate aminotransferase (EC 2.6.1.1), Human s a metabolic regulator with the highest activity in the heart, liver and skeletal muscle. Aspartate aminotransferase, Human (HEK293) comprises two isozymes: the cytoplasmic form (AST1) and the mitochondrial form (AST2). By catalyzing reversible transamination reactions between oxaloacetate, L-glutamate and other substances, it is deeply involved in key physiological processes such as amino acid metabolism, the tricarboxylic acid cycle and neurotransmitter synthesis. Aspartate aminotransferase, Human also provides substrate support for the synthesis of urea and purines/pyrimidines. Aspartate aminotransferase, Human is a serum marker reflecting cardiac and hepatic injury, and its abnormal levels are also closely associated with myocardial infarction, cardiovascular diseases and various cancers .
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1 Cited Publications
Cat. No.: HY-P7611
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: GOT1; Aspartate Transaminase 1; Glutamic-Oxaloacetic Transaminase 1; Transaminase A; Glutamate Oxaloacetate Transaminase 1; CAspAT; AST1; CCAT; SGOT; Glutamic-Oxaloacetic Transaminase 1, Soluble (Aspartate Aminotransferase 1); AST; Testis Secretory Sperm-
Species:
Human
Source:
E. coli
Synonyms: EC 2.6.1.1, Human liver; GOT, Human liver; AST, Human liver
Research Areas:
Aspartate aminotransferase (EC 2.6.1.1), Human liver is a metabolic regulator with the highest activity in the heart, liver and skeletal muscle. Aspartate aminotransferase, Human liver comprises two isozymes: the cytoplasmic form (AST1) and the mitochondrial form (AST2). By catalyzing reversible transamination reactions between oxaloacetate, L-glutamate and other substances, it is deeply involved in key physiological processes such as amino acid metabolism, the tricarboxylic acid cycle and neurotransmitter synthesis. Aspartate aminotransferase, Human liver also provides substrate support for the synthesis of urea and purines/pyrimidines. Aspartate aminotransferase, Human liver is a serum marker reflecting cardiac and hepatic injury, and its abnormal levels are also closely associated with myocardial infarction, cardiovascular diseases and various cancers .
Cat. No.: HY-176192
Research Areas:
SMU-14a is a selective Toll-like receptor 3 (TLR3) inhibitor wirh an IC50 of 0.18 μM. SMU-14a reduces phosphorylation of p65, ERK, and TBK1 via NF-κB, MAPK, and IRF3 signaling pathways. SMU-14a inhibits IL-6 secretion in mouse peritoneal macrophages, downregulates TNF-α in human peripheral blood monocytes and decreases serum alanine aminotransferase (ALT) and aspartate aminotransferase (AST) levels. SMU-14a can be used for the research of acute hepatitis .
Cat. No.: HY-P85630
Synonyms: AATM_Human; AL022787; Aspartate aminotransferase; Aspartate aminotransferase 2; Aspartate aminotransferase, mitochondrial; ASPATA; FABP 1; FABP pm; FABP-1; FABPpm; Fatty acid binding protein; Fatty acid-binding protein; FLJ40994; Glutamate oxaloacetate transaminase 2; Glutamate oxaloacetate transaminase 2, mitochondrial; Glutamate oxaloacetate transaminase, mitochondrial; Glutamic oxaloacetic transaminase 2, mitochondrial; Aspartate aminotransferase 2; Got 2; GOT2; KAT4; KATIV; Kynurenine aminotransferase IV; mAspAT; MGC102129; MGC115763; mitAAT; mitochondrial; Mitochondrial Aspartate aminotransferase; OTTMUSP00000017748; Plasma membrane fatty acid binding protein; Plasma membrane-associated fatty acid-binding protein; Transaminase A.
Cat. No.: HY-P705711
Purity: ≥ 90%, as determined by reducing SDS-PAGE .
Synonyms: Aspartate aminotransferase, mitochondrial; EC:2.6.1.1; EC:2.6.1.7; mAspAT; Fatty acid-binding protein (FABP-1); Glutamate oxaloacetate transaminase 2; ; Kynurenine aminotransferase 4; ; Kynurenine aminotransferase IV; Kynurenine--oxoglutarate transaminase 4; GOT2; KYAT4; Plasma membrane-associated fatty acid-binding protein (FABPpm); Transaminase A
Species:
Human
Source:
E. coli
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
