5 Results for "

CD34+ bone marrow progenitor cells

" in MedChemExpress (MCE) Product Catalog:
Products (5)

5 Results for "CD34+ bone marrow progenitor cells" in MCE Product Catalog:

2
2 Cited Publications
Cat. No.: HY-19867A
CAS No.: 1191450-19-7
Synonyms: TG-0054 hydrobromide
Target:  

CXCR

Research Areas:  

Cardiovascular Disease Cancer

Burixafor (TG-0054) hydrobromide is a potent CXCR4 antagonist with a pIC50 of 7.4. Burixafor hydrobromide inhibits the binding of CXCL12 to CXCR4, antagonizes CXCL12-induced recruitment of Gαᵢ and β-arrestin2, and blocks the downstream Gαᵢ-mediated inhibitory effect on cAMP signal transduction. Burixafor hydrobromide mobilizes CD34 + hematopoietic stem/progenitor cells (HSPC) from the bone marrow to the peripheral blood. Burixafor hydrobromide can be used for research on autologous hematopoietic stem cell transplantation (ASCT) .
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Cat. No.: HY-P1104A
CAS No.: 842166-42-1
Target:  

CXCR Akt Apoptosis

Research Areas:  

Cardiovascular Disease Cancer

FC131 TFA is a CXCR4 antagonist that inhibits AKT kinase activity in AML OCI-AML3 cells. D-ArgFC131, a derivative of FC131 TFA, inhibits the phosphorylation of downstream ERK1/2 and Akt, induces caspase-3 pathway-mediated apoptosis, and causes cell cycle arrest. FC131 TFA exerts cytotoxic effects in cancer cells such as AML cells. FC131 TFA is applicable for cancer-related research .
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Cat. No.: HY-P1104
CAS No.: 606968-52-9
Target:  

CXCR Akt Apoptosis

Research Areas:  

Cardiovascular Disease Cancer

FC131 is a CXCR4 antagonist that inhibits AKT kinase activity in AML OCI-AML3 cells. D-ArgFC131, a derivative of FC131, inhibits the phosphorylation of downstream ERK1/2 and Akt, induces caspase-3 pathway-mediated apoptosis, and causes cell cycle arrest. FC131 exerts cytotoxic effects in cancer cells such as AML cells. FC131 is applicable for cancer-related research .
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Cat. No.: HY-19867
CAS No.: 1191448-17-5
Synonyms: TG-0054
Target:  

CXCR

Research Areas:  

Cancer

Burixafor (TG-0054) is a potent CXCR4 antagonist with a pIC50 of 7.4. Burixafor inhibits the binding of CXCL12 to CXCR4, antagonizes CXCL12-induced recruitment of Gαᵢ and β-arrestin2, and blocks the downstream Gαᵢ-mediated inhibitory effect on cAMP signal transduction. Burixafor mobilizes CD34 + hematopoietic stem/progenitor cells (HSPC) from the bone marrow to the peripheral blood. Burixafor can be used for research on autologous hematopoietic stem cell transplantation (ASCT) .
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Cat. No.: HY-182501
CAS No.: 1015855-72-7
Research Areas:  

Cardiovascular Disease

HSC mobilizer-1 (Compound 3) is an in vitro expansion activator of HSC. HSC mobilizer-1 promotes the in vitro expansion of hematopoietic stem cells .
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