2 Results for "

CDK6 ligand 1

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "CDK6 ligand 1" in MCE Product Catalog:

Cat. No.: HY-180278
Research Areas:  

Cancer

CDK6 ligand 1 is a CDK6 ligand that can be used in studies related to PROTAC synthesis, for example, acting as the target protein ligand of PROTAC CDK6 Degrader 1 (HY-180277) .
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Cat. No.: HY-130296
CAS No.: 2366269-23-8
Purity:  95.23%
Synonyms: PROTAC CDK6 ligand 1
Research Areas:  

Cancer

Palbociclib-propargyl is a ligand for target protein CDK6 for PROTAC, and binds to CRBN ligand via a PEG linker to make a PROTAC CP-10. CP-10 shows a DC50 of 2.1 nM for CDK6 . Palbociclib-propargyl is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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