Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
31 Results for "
Ca2 -CaM
" in MedChemExpress (MCE) Product Catalog:
Products (31)
31 Results for "Ca2 -CaM" in MCE Product Catalog:
37
37 Publications Verification
Cat. No.: HY-19805
CAS No.: 52029-86-4
Research Areas:
STO-609 is a selective and cell-permeable inhibitor of the Ca 2+/calmodulin-dependent protein kinase kinase (CaM-KK), with Ki values of 80 and 15 ng/mL for recombinant CaM-KKα and CaM-KKβ, respectively. STO-609 inhibits AMP-activated protein kinase kinase (AMPKK) activity in HeLa cell lysates with an IC50 ~0.02 g/ml.
5
Target:
Research Areas:
Calmidazolium chloride (R 24571) is a calmodulin antagonist, antagonizing CaM-dependent phosphodiesterase and calmodulin-induced activation of erythrocyte Ca2+-transporting ATPase with IC50s of 0.15 and 0.35 μM, respectively . Also in anti-cancer research . Calmidazolium binds to calmodulin with a Kd of 3 nM.
3
3 Cited Publications
Cat. No.: HY-P1077
CAS No.: 145224-99-3
Research Areas:
3
3 Cited Publications
Cat. No.: HY-P1077A
Research Areas:
2
2 Cited Publications
Cat. No.: HY-P1075
CAS No.: 261969-05-5
Target:
Research Areas:
2
2 Cited Publications
Cat. No.: HY-P0271A
Target:
Research Areas:
1
1 Cited Publications
Target:
Research Areas:
Calmodulin antagonist-1 (A-5) is a calmodulin (CaM) antagonist. Calmodulin antagonist-1 inhibits calmodulin-activated Ca 2+-phosphodiesterase (PDE) (IC50=66 μM). Calmodulin antagonist-1 also inhibits trypsin-treated Ca 2+-PDE (IC50=560 μM) in a competitive fashion with respect to cyclic GMP .
Synonyms: CGS-9343B; KW 5617
Target:
Research Areas:
Neurological Disease Metabolic Disease Inflammation/Immunology
Zaldaride maleate (CGS-9343B) is a potent, orally active and selective inhibitor of calmodulin. Zaldaride maleate inhibits CaM (calmodulin)-stimulated cAMP phosphodiesterase activity, with an IC50 of 3.3 nM . Zaldaride maleate prevents estrogen-induced transcription activation by ER, reversibly blocks voltage-activated Na +, Ca 2+ and K + currents in PC12 cells and inhibits nAChR .
Cat. No.: HY-P1805
CAS No.: 104041-80-7
Target:
Research Areas:
Cat. No.: HY-P1076A
Target:
Research Areas:
Cat. No.: HY-P991646
Synonyms: heMab
Target:
Research Areas:
Cat. No.: HY-19805A
CAS No.: 1173022-21-3
Research Areas:
STO-609 acetate is a selective and cell-permeable inhibitor of the Ca 2+/calmodulin-dependent protein kinase kinase (CaM-KK), with Ki values of 80 and 15 ng/mL for recombinant CaM-KKα and CaM-KKβ, respectively. STO-609 acetate inhibits AMP-activated protein kinase kinase (AMPKK) activity in HeLa cell lysates with an IC50 ~0.02 g/ml.
Cat. No.: HY-P5436
CAS No.: 99268-57-2
Cat. No.: HY-19025
CAS No.: 86384-98-7
Target:
Research Areas:
CV-159 is a unique dihydropyridine Ca 2+ antagonist with an anti-calmodulin (CaM) action, and has antiinflammatory activities.
Cat. No.: HY-P0271
CAS No.: 108334-68-5
Research Areas:
Cat. No.: HY-P10316
CAS No.: 205598-38-5
Synonyms: Calmodulin-Dependent Protein Kinase I (299-320) Binding Domain
Cat. No.: HY-142087
CAS No.: 76265-41-3
Category:
Target:
Cat. No.: HY-P1076
CAS No.: 261969-04-4
Target:
Research Areas:
Cat. No.: HY-P2471
Target:
Research Areas:
Cat. No.: HY-P1075A
Target:
Research Areas:
- 1
- 2
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
