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Results for "

Candida krusei

" in MedChemExpress (MCE) Product Catalog:

5

Inhibitors & Agonists

1

Natural
Products

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-19377
    SS-750

    		Fungal Cytochrome P450 Infection
    SS-750 is an orally active Triazole derivative and antifungal agent. SS-750 binds to fungal cytochrome P450. SS-750 shows antifungal activities against Candida species and C. neoformans strains tested. SS750 shows MIC90 values of 0.25, 1, and 2 μg/mL against Candida parapsilosis, C. krusei, and C. glabrata, respectively. SS-750 improves systemic and pulmonary candidiasis caused by C. albicans .
    SS-750
  • HY-136755
    CYP51-IN-5

    		Cytochrome P450 Fungal Infection
    CYP51-IN-5 is a cytochrome P450 14α-demethylase (CYP51) inhibitor and an antifungal (fungal) agent belonging to the triazole derivative class. CYP51-IN-5 is applicable to the research of Candida albicans, Cryptococcus neoformans, Candida parapsilosis, Candida tropicalis, Trichophyton rubrum, Candida krusei and Microsporum gypseum .
    CYP51-IN-5
  • HY-136753
    Antifungal agent-162

    		Fungal Infection
    Antifungal agent-162 (Compound 1c) is an Antifungal agent. Antifungal agent-162 exhibits potent in vitro antifungal activity against Candida albicans, Cryptococcus neoformans, Candida parapsilosis, Candida tropicalis, Candida krusei, and Microsporum gypseum (with MIC80 values ranging from 0.0156 to 0.25 μg/mL), while shows no activity against Aspergillus fumigatus .
    Antifungal agent-162
  • HY-125459
    L 705589

    		Fungal Infection
    L-705589 is a semi-synthetic penicillin-type antifungal agent. L-705589 exerts its antifungal effect by inhibiting the 1,3-β-D-glucan synthase in the fungal cell wall. L-705589 exhibits potent bactericidal activity against various Candida species (such as Candida albicans, Candida glabrata, Candida krusei, etc.) (MFC: 0.06 - 8 μg/mL), but has relatively weak activity against Cryptococcus neoformans (MFC: 32 - 64 μg/mL). L-705589 remains active against drug-resistant Candida strains and is not prone to inducing drug resistance. L-705589 significantly improves survival rates in the model of minor invasive aspergillosis .
    L 705589
  • HY-N19506
    Vincadifformine N(4)-oxide

    		Fungal Infection
    Vincadifformine N (4)-oxide is a monoterpenoid indole alkaloid. Vincadifformine N (4)-oxide can be isolated from Rhazya stricta. Vincadifformine N (4)-oxide shows a MIC > 50 μg/mL against tested Candida strains and exhibits no antifungal activity .
    Vincadifformine N(4)-oxide

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