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Cat. No.: HY-N21986

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Antifungal agent 177

Antifungal agent 177 is a novel steroidal saponin found in the rhizomes of Paris polyphylla Smith. Antifungal agent 177 exhibits antifungal activity against Cladosporium cladosporioides, with a liquid MIC of 50 μg/mL against Candida albicans. Antifungal agent 177 is applicable to research related to fungal infections.

For research use only. We do not sell to patients.

CAS No.: 1096965-33-1
Formula: C₄₉H₇₈O₂₁
Molecular Weight:1003.13

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Antifungal agent 177 Chemical Structure

CAS No.: 1096965-33-1

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vitro
Chemical Information
Purity & Documentation
References
Calculators
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Classifications
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Biological Activity

Description

In Vitro

Antifungal agent 177 (Saponin 2) (0.01-280 μg; 48-72 h) inhibits the growth of Cladosporium cladosporioides at concentrations of 9 μg and above, and completely suppresses its growth at a concentration of 280 μg^[1].
Antifungal agent 177 (24 h) inhibits the growth of C. albicans IFO 1060, with an MIC of 50 μg/mL^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 1096965-33-1
Molecular Weight 1003.13
Formula C₄₉H₇₈O₂₁
SMILES

[H][C@]1(C[C@@]2(O[C@]3([C@H]([C@@]24O)C)OC[C@@H](CC3)C)[H])[C@@]5(CC=C6C[C@@H](O[C@@H]7O[C@@H]([C@H]([C@@H]([C@H]7O[C@@H]8O[C@H]([C@@H]([C@H]([C@H]8O)O)O)C)O)O[C@H]9[C@@H]([C@H]([C@@H](O9)CO[C@@H]%10OC[C@H]([C@@H]([C@H]%10O)O)O)O)O)CO)CC[C@@]6([C@@](CC[C@@]14C)5[H])C)[H]
Structure Classification
- Steroids
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Deng D, et al. Antifungal saponins from Paris polyphylla Smith. Planta medica. 2008 Sep;74(11):1397-402.

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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