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Cereblon ligand-2

" in MedChemExpress (MCE) Product Catalog:
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Cat. No. Nombre del producto Target Áreas de investigación Chemical Structure
  • HY-103596
    Thalidomide-4-OH

    Cereblon ligand 2; E3 ligase ligand 2

    		 Ligands for E3 Ligase Autophagy Apoptosis Cancer
    Thalidomide-4-OH (Cereblon ligand 2) is the Thalidomide-based Cereblon ligand used in the recruitment of CRBN protein. Thalidomide-4-OH (Cereblon ligand 2) can be connected to the ligand for protein by a linker to form PROTACs .
    Thalidomide-4-OH
  • HY-W674436
    (S)-Thalidomide-4-OH

    		Drug Isomer Cancer
    (S)-Thalidomide-4-OH is the S-isomer of Thalidomide-4-OH (HY-103596). Thalidomide-4-OH (Cereblon ligand 2) is the Thalidomide-based Cereblon ligand used in the recruitment of CRBN protein. Thalidomide-4-OH (Cereblon ligand 2) can be connected to the ligand for protein by a linker to form PROTACs .
    (S)-Thalidomide-4-OH
  • HY-103596R
    Thalidomide-4-OH (Standard)

    Cereblon ligand 2 (Standard); E3 ligase ligand 2 (Standard)

    		 Ligands for E3 Ligase Autophagy Apoptosis Reference Standards Cancer
    Thalidomide-4-OH (Standard) is the analytical standard of Thalidomide-4-OH (HY-103596). This product is intended for research and analytical applications. Thalidomide-4-OH (Cereblon ligand 2) is the Thalidomide-based Cereblon ligand used in the recruitment of CRBN protein. Thalidomide-4-OH (Cereblon ligand 2) can be connected to the ligand for protein by a linker to form PROTACs .
    Thalidomide-4-OH (Standard)
  • HY-161961
    Thalidomide-NH-C10-Boc

    		E3 Ligase Ligand-Linker Conjugates Cancer
    Thalidomide-NH-C10-Boc (compound S20) is a conjugate of the E3 ubiquitinase ligand Thalidomide and PROTAC Linker, which can recruit Cereblon ubiquitinase. Thalidomide-NH-C10-Boc can couple the target protein ligand through the PTOTAC Linker to synthesize PROTAC molecules with degradation effects. For example, Thalidomide-NH-C10-Boc can couple with the ligand EP300/CBP ligand 2 (HY-161960) to produce the PROTAC molecule dCE-2 (HY-161958) .
    Thalidomide-NH-C10-Boc
  • HY-176125
    E3 Ligase Ligand-linker Conjugate 184

    		E3 Ligase Ligand-Linker Conjugates Cancer
    E3 Ligase Ligand-linker Conjugate 184 is a E3 Ligase Ligand-Linker Conjugates, consisting of CDK2 ligand-2 (HY-176124) and the corresponding Linker. E3 Ligase Ligand-linker Conjugate 184 can serve as a Cereblon ligand to recruit CRBN protein and serve as a key intermediate for the synthesis of complete CDK2 degrader 2 (HY-163815) .
    E3 Ligase Ligand-linker Conjugate 184

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