Thalidomide-NH-C10-Boc
Thalidomide-NH-C10-Boc (compound S20) is a conjugate of the E3 ubiquitinase ligand Thalidomide and PROTAC Linker, which can recruit Cereblon ubiquitinase. Thalidomide-NH-C10-Boc can couple the target protein ligand through the PTOTAC Linker to synthesize PROTAC molecules with degradation effects. For example, Thalidomide-NH-C10-Boc can couple with the ligand EP300/CBP ligand 2 (HY-161960) to produce the PROTAC molecule dCE-2 (HY-161958).
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- CAS No.: 2428400-25-1
- Formula: C28H39N3O6
- Molecular Weight:513.63
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
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All E3 Ligase Ligand-Linker Conjugates Isoforms
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Biological Activity
Chemical Information
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CAS No. 2428400-25-1
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Molecular Weight 513.63
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Formula C28H39N3O6
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SMILES
O=C(N1C2CCC(NC2=O)=O)C3=CC=CC(NCCCCCCCCCCC(OC(C)(C)C)=O)=C3C1=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Thalidomide-NH-C10-Boc Related Classifications
HY-161961 Related Classifications
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