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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
198 Results for "
Crosslinker
" in MedChemExpress (MCE) Product Catalog:
Products (198)
198 Results for "Crosslinker" in MCE Product Catalog:
16
16 Publications Verification
Cat. No.: HY-W019543
CAS No.: 68528-80-3
Research Areas:
Disuccinimidyl suberate Crosslinker is an amine-reactive bifunctional protein crosslinker. Disuccinimidyl suberate Crosslinker enables stable protein-protein, peptide, and biomolecule conjugation.
9
9 Cited Publications
Synonyms: EGS Crosslinker
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EGNHS is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs .
8
8 Cited Publications
Synonyms: HOSu; 1-Hydroxy-2,5-pyrrolidinedione
5
5 Cited Publications
Synonyms: Disuccinimidyl glutarate
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DSG Crosslinker is an amine-reactive and noncleavable protein crosslinker. DSG Crosslinker enables stable protein-protein, peptide, and biomolecule conjugation.
5
5 Cited Publications
Cat. No.: HY-D0975
CAS No.: 92921-24-9
5
5 Cited Publications
Synonyms: SPDP Crosslinker; Py-ds-Prp-OSu
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SPDP (SPDP Crosslinker) is a short-chain crosslinker for amine-to-sulfhydryl conjugation via NHS-ester and pyridyldithiol reactive groups that form cleavable (reducible) disulfide bonds with cysteine sulfhydryls. It is a glutathione cleavable ADC linker used for the antibody-drug conjugates (ADCs) .
3
3 Cited Publications
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BS3 Crosslinker is a cell-impermeable NHS ester crosslinker. BS3 Crosslinker "covalently locks" two spatially adjacent proteins on the surface of living cells into a covalent complex, and the dimerization/oligomerization status is determined by observing molecular weight shifts via Western blot. BS3 Crosslinker can crosslink EGFR and c-MET to assist in detecting and evaluating their dimerization status. It can be used in research related to oral cancer and glioblastoma .
3
3 Cited Publications
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DSP Crosslinker is an amine-reactive and cleavable protein crosslinker. DSP Crosslinker enables stable protein-protein, peptide, and biomolecule conjugation.
3
3 Cited Publications
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Research Areas:
BS3 Crosslinker disodium is a cell-impermeable NHS ester crosslinker. BS3 Crosslinker disodium "covalently locks" two spatially adjacent proteins on the surface of living cells into a covalent complex, and the dimerization/oligomerization status is determined by observing molecular weight shifts via Western blot. BS3 Crosslinker disodium can crosslink EGFR and c-MET to assist in detecting and evaluating their dimerization status. It can be used in research related to oral cancer and glioblastoma .
3
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Trioxsalen (Trisoralen), a psoralen derivative, is a photochemical DNA crosslinker. Trioxsalen only works after photoactivation with near ultraviolet light. Trioxsalen is a photosensitizer that can be used for the research of vitiligo and hand eczema. Trioxsalen is used for visualization of genomic interstrand cross-links localized by laser photoactivation .
2
2 Cited Publications
Synonyms: DSSeb; Sebacic acid bis N-succinimidyl ester
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Disuccinimidyl sebacate (DSSeb) is a cross-linker that can be used in the synthesis of the intermolecular cross-linked peptides .
2
2 Cited Publications
Cat. No.: HY-166648A
DSPE-PEG-Maleimide ammonium (MW 2000) is a functional lipid component and a thiol-reactive crosslinker. DSPE-PEG-Maleimide ammonium (MW 2000) undergoes Michael addition with the thiol groups of thiolated or cyclic RGD peptides to form stable thioether bonds and DSPE-PEG (2000)-RGD. DSPE-PEG-Maleimide ammonium (MW 2000) is applicable to research on drug delivery .
2
2 Cited Publications
Cat. No.: HY-166648
2
2 Cited Publications
Synonyms: Bisacrylamide; MBA; Methylenebisacrylamide; N,N-Methylenebisacrylamide
2
1
1 Cited Publications
Cat. No.: HY-42360
CAS No.: 64987-85-5
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SMCC is a protein crosslinker. SMCC contains an amine-reactive N-hydroxysuccinimide ester and a sulfhydryl-reactive maleimide group that can be used in the conjugation of proteins. SMCC-conjugated antigen coupled spleen cells to induce antigen-specific immune responses .
1
1 Cited Publications
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AMAS is a nonclaevable heterobifunctional crosslinker with NHS ester and maleimide groups that allows covalent conjugation of amine- and sulfhydryl-containing molecules.
1
1 Cited Publications
Cat. No.: HY-W123005
CAS No.: 58537-94-3
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Dimethyl pimelimidate dihydrochloride is a bifunctional imidoester protein-protein crosslinker used in chromatin immunoprecipitation (ChIP) assays .
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DTSSP Crosslinker is a crosslinker reactive with primary amines. DTSSP Crosslinker is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
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Azide-A-DSBSO crosslinker is a mass spectrometry (MS) cleavable, membrane permeable, homobifunctional, azide-labeled, acid-cleavable crosslinking peptide. Azide-A-DSBSO crosslinker crosslinks proteins via NHS ester reaction with lysine residues. Azide-A-DSBSO crosslinker can be used to study protein-protein interactions by cross-linking mass spectrometry (XL-MS) [1] .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
