Casein
Based on 2 publication(s) in Google Scholar
Casein is an orally active phosphoprotein that can be separated into various electrophoretic components, such as α2-Casein, κ-Casein, β-casein, and γ-casein. Casein has also been blended and grafted with other polymers, cross-linkers, or monomers to improve its functional properties. Casein enhances calcium absorption and reduces the extent of fissure as well as smooth-surface caries. Casein promotes proliferation of prostate cancer. Casein has various applications in the paper, leather, textile, and food industries, serving as coatings, adhesives, and packaging materials.
For research use only. We do not sell to patients.
- Purity: 97.40%
- CAS No.: 9000-71-9
- Formula: C81H125N22O39P
- Molecular Weight:2061.96
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Publications Citing Use of MedChemExpress (MCE) Casein
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Customer Validation & Images
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Bio/Physico-chemical Assay
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Bio/Physico-chemical Assay
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Bio/Physico-chemical Assay
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Bio/Physico-chemical Assay
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Bio/Physico-chemical Assay
All Endogenous Metabolite Isoforms
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Biological Activity
Casein (500 ppm, p.o., 2 weeks) enhances calcium absorption in the rat[5].
Casein (2% (w/v), in drinking water, p.o.) reduces the extent of fissure and smooth-surface caries of male Sprague-Dawley rats consuming a solid cariogenic diet[6].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
Chemical Information
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CAS No. 9000-71-9
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Appearance Solid
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Molecular Weight 2061.96
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Formula C81H125N22O39P
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Color Off-white to yellow
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SMILES
[Casein]
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Publications (2)
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Journal Impact Factor
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Most Recent
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Int J Biol Macromol
Dynamic catalytic domain plasticity governs substrate specificity in industrial serine proteases: Structural and functional implications. [Abstract]2025 Oct 17;331(Pt 1):148374. PMID: 41110577 -
Talanta
Phenylboronic acid decorated SiO2@Fe3O4 magnetic nanoparticle coupled with peroxidase-like Au,Pt,Cu@polydopamine immunoprobe based sandwich approach for the detection of transferrin. [Abstract]2025 Aug 26;297(Pt B):128747. PMID: 40885136
Casein purchased from MedChemExpress. Usage Cited in: Talanta. 2025 Aug 26;297(Pt B):128747. [Abstract]
Adsorption performance of PBA-SiO2@Fe3O4 toward TRF after blocking with different concentrations of Casein (0.1 %-1 %).
Casein purchased from MedChemExpress. Usage Cited in: Talanta. 2025 Aug 26;297(Pt B):128747. [Abstract]
Adsorption performance of PBA-SiO2@Fe3O4 toward TRF after blocking with Casein (1 %).
Casein purchased from MedChemExpress. Usage Cited in: Talanta. 2025 Aug 26;297(Pt B):128747. [Abstract]
Adsorption performance of PBA-SiO2@Fe3O4 toward various glycoproteins utilizingCasein (1 %).
Casein purchased from MedChemExpress. Usage Cited in: Talanta. 2025 Aug 26;297(Pt B):128747. [Abstract]
Adsorption performance of PBA-SiO2@Fe3O4 toward various glycoproteins utilizingCasein (0.1 %-1 %).
Casein purchased from MedChemExpress. Usage Cited in: Talanta. 2025 Aug 26;297(Pt B):128747. [Abstract]
Casein (0.1 %; 400 μL) did not occupy the PBA binding sites responsible for interaction with sugar residues in TRF, as suggested by the negligible impact of increasing glucose concentrations on its blocking effect.
Solvent & Solubility
0.1 M NaOH : 20 mg/mL (9.70 mM; ultrasonic and warming and heat to 60°C)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (276 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
[1]. Ghosh A, et al. Effect of cross-linking on microstructure and physical performance of casein protein. Biomacromolecules. 2009;10(7):1681-1688. [Content Brief]
[2]. Park SW, et al. A milk protein, casein, as a proliferation promoting factor in prostate cancer cells. World J Mens Health. 2014 Aug;32(2):76-82. [Content Brief]
[3]. Rosenberg E, et al. Cell density-dependent growth of Myxococcus xanthus on casein. J Bacteriol. 1977 Feb;129(2):770-7. [Content Brief]
[4]. Lillefosse HH, et al. Hydrolyzed casein reduces diet-induced obesity in male C57BL/6J mice. J Nutr. 2013 Sep;143(9):1367-75. [Content Brief]
[5]. Bennett T, et al. The effect of high intakes of casein and casein phosphopeptide on calcium absorption in the rat. Br J Nutr. 2000 Jun;83(6):673-80. [Content Brief]
[6]. Reynolds EC, et al. Effect of casein and whey-protein solutions on caries experience and feeding patterns of the rat. Arch Oral Biol. 1984;29(11):927-33. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
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| 0.1 M NaOH | 1 mM | 0.4850 mL | 2.4249 mL | 4.8498 mL | 12.1244 mL |
| 5 mM | 0.0970 mL | 0.4850 mL | 0.9700 mL | 2.4249 mL |
Casein Related Classifications
HY-125865 Related Classifications
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