110-26-9
110-26-9
Chemical Structure
N,N'-Methylenebisacrylamide
Synonym(s): Bisacrylamide; MBA; Methylenebisacrylamide; N,N-Methylenebisacrylamide
- CAS No.: 110-26-9
- Formula:C7H10N2O2
- Molecular Weight:154.17
IUPAC Name: N,N'-methylenediacrylamide
InChIKey: ZIUHHBKFKCYYJD-UHFFFAOYSA-N
SMILES: C=CC(NCNC(C=C)=O)=O
Biological Activity: N,N'-Methylenebisacrylamide (Bisacrylamide) is an orally active acrylamide dimer and crosslinker. N,N'-Methylenebisacrylamide increases CYP2E1, P53, cleaved caspase-3. N,N'-Methylenebisacrylamide promotes hepatic cancer. N,N'-Methylenebisacrylamide changes sperm abnormality rate and sperm count. N,N'-Methylenebisacrylamide decreases the number of various cells in the blood as well as induces liver and testicular damage. N,N'-Methylenebisacrylamide is used to prepare polyacrylamide gel[1][2][3][4][5][6][7].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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N,N'-Methylenebisacrylamide | 99.98% | N,N'-Methylenebisacrylamide (Bisacrylamide) is an orally active acrylamide dimer and crosslinker. N,N'-Methylenebisacrylamide increases CYP2E1, P53, cleaved caspase-3. N,N'-Methylenebisacrylamide promotes hepatic cancer. N,N'-Methylenebisacrylamide changes sperm abnormality rate and sperm count. N,N'-Methylenebisacrylamide decreases the number of various cells in the blood as well as induces liver and testicular damage. N,N'-Methylenebisacrylamide is used to prepare polyacrylamide gel. | ||||||||||||||||||||
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N,N'-Methylenebisacrylamide-d6 | N,N'-Methylenebisacrylamide-d6 is the deuterium labeled N,N'-Methylenebisacrylamide (HY-D0848). N,N'-Methylenebisacrylamide (Bisacrylamide) is an orally active acrylamide dimer and crosslinker. N,N'-Methylenebisacrylamide increases CYP2E1, P53, cleaved caspase-3. N,N'-Methylenebisacrylamide promotes hepatic cancer. N,N'-Methylenebisacrylamide changes sperm abnormality rate and sperm count. N,N'-Methylenebisacrylamide decreases the number of various cells in the blood as well as induces liver and testicular damage. N,N'-Methylenebisacrylamide is used to prepare polyacrylamide gel. | |||||||||||||||||||||
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3-Methylcrotonylglycine | 98.67% | 3-Methylcrotonylglycine is an organic acid conjugate associated with leucine catabolism that inhibits respiratory chain complex II-III, mitochondrial creatine kinase, and synaptic membrane Na+, K+-ATPase. 3-Methylcrotonylglycine increases reactive oxygen species levels to mediate oxidative damage, while inhibiting mitochondrial electron transport, reducing tricarboxylic acid cycle flux, and interfering with intracellular energy transport and neuronal ion homeostasis. 3-Methylcrotonylglycine is a neurotoxic metabolite that accumulates in the metabolic pathway of 3-methylcrotonyl-CoA carboxylase deficiency. 3-Methylcrotonylglycine can be used in studies related to 3-methylcrotonyl-CoA carboxylase deficiency. | ||||||||||||||||||||
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Maleuric acid | 95.0% | Maleuric acid has cytotoxicity on Ehrlich ascites tumor cells by preventing the entry of preprophase cells into mitosis. | ||||||||||||||||||||
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Apronal (Standard) | 99.85% | Apronal (Standard) is the analytical standard of Apronal. This product is intended for research and analytical applications. Apronal (Allylisopropylacetylurea, Apronalide) can bu used for the research of neuropsychiatry disorders. | ||||||||||||||||||||
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Dichlormid (Standard) | ≥98% | Dichlormid (Standard) is the analytical standard of Dichlormid. This product is intended for research and analytical applications. Dichlormid is a herbicide safener. Dichlormid up-regulates expression of ZmGST27 and ZmMRP1 and increases ZmGT1. | ||||||||||||||||||||
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N-(2-Hydroxyethyl)acrylamide | 99.95% | N-(2-Hydroxyethyl)acrylamide is an amphiphilic polymer that can be used to prepare hydrogels. | ||||||||||||||||||||
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2-(2-Acetamidoacetamido)acetic acid | 99.89% | 2-(2-Acetamidoacetamido)acetic acid (N-Acetylglycylglycine) is a biochemical reagent that can be used as a biological material or organic compound for life science related research. | ||||||||||||||||||||
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N,N'-Diacryloylpiperazine | 98.0% | N,N'-Diacryloylpiperazine can be used to synthesize bioconjugates and other compounds, and can also be used in the fields of medicine and biotechnology. N,N'-Diacryloylpiperazine is a biomaterial or organic compound that can be used for life science research. | ||||||||||||||||||||
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(3-Acrylamidopropyl)trimethylammonium chloride | (3-Acrylamidopropyl)trimethylammonium chloride is a biochemical reagent that can be used as a biological material or organic compound for life science related research. | |||||||||||||||||||||
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N,N'-(Ethane-1,2-diyl)bis(2-bromoacetamide) | ≥95.0% | N,N'-(Ethane-1,2-diyl)bis(2-bromoacetamide) is a PROTAC linker that can be used in the synthesis of PROTACs. | ||||||||||||||||||||
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N-Acetylglycine (Standard) | ≥98% | N-Acetylglycine (Standard) (Aceturic acid (Standard)) is the analytical standard of N-Acetylglycine (HY-Y0069). This product is intended for research and analytical applications. N-Acetylglycine (Aceturic acid) is a minor constituent of numerous foods. N-Acetylglycine is a flavor enhancer which elicits Monosodium glutamate (MSG)-like sensory experiencesN-Acetylglycine. | ||||||||||||||||||||
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References
- [1]. Atia MM, et al. Nanocurcumin and curcumin prevent N, N'-methylenebisacrylamide-induced liver damage and promotion of hepatic cancer cell growth. Sci Rep. 2022 May 18;12(1):8319. [Content Brief]
- [2]. George JD, et al. Evaluation of the developmental toxicity of methacrylamide and N,N'-methylenebisacrylamide in Swiss mice. Toxicol Sci. 1998 Nov;46(1):124-33. [Content Brief]
- [3]. de Souza Pereira R. Comparison of biochemical effects produced by calcium ions and by monomers of polyacrylamide (acrylamide and bisacrylamide) on strains of Saccharomyces cerevisiae used for production of chiral synthons. Mol Cell Biochem. 1998 Jan;178(1-2):33-40. [Content Brief]
- [4]. Atia M M, et al. The immunomodulatory role of curcumin and its nanoparticles in mice testis exposed to N, N'-methylenebisacrylamide. Egyptian Academic Journal of Biological Sciences, B. Zoology, 2022, 14(1): 39-54.
- [5]. Atia MM, et al. Rehabilitation of N, N'-methylenebisacrylamide-induced DNA destruction in the testis of adult rats by adipose-derived mesenchymal stem cells and conditional medium. Heliyon. 2024 Nov 14;10(23):e40380. [Content Brief]
- [6]. Sakamoto J, et al. Effects of N,N'-methylene-bis-acrylamide (MBA) on mouse germ cells--sperm count and morphology, and testicular pathology. Arch Toxicol. 1988 Aug;62(1):54-9. [Content Brief]
- [7]. Hashimoto K, et al. Anemia and porphyria caused by N,N'-methylene-bis-acrylamide (MBA) in mice and rats. Arch Toxicol. 1982 May;50(1):47-55. [Content Brief]
