110-26-9
Chemical Structure
N,N'-Methylenebisacrylamide
Synonym(s): Bisacrylamide; MBA; Methylenebisacrylamide; N,N-Methylenebisacrylamide
- CAS No.: 110-26-9
- Formula:C7H10N2O2
- Molecular Weight:154.17
IUPAC Name: N,N'-methylenediacrylamide
InChIKey: ZIUHHBKFKCYYJD-UHFFFAOYSA-N
SMILES: C=CC(NCNC(C=C)=O)=O
Biological Activity: N,N'-Methylenebisacrylamide (Bisacrylamide) is an orally active acrylamide dimer and crosslinker. N,N'-Methylenebisacrylamide increases CYP2E1, P53, cleaved caspase-3. N,N'-Methylenebisacrylamide promotes hepatic cancer. N,N'-Methylenebisacrylamide changes sperm abnormality rate and sperm count. N,N'-Methylenebisacrylamide decreases the number of various cells in the blood as well as induces liver and testicular damage. N,N'-Methylenebisacrylamide is used to prepare polyacrylamide gel[1][2][3][4][5][6][7].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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N,N'-Methylenebisacrylamide | 99.98% | N,N'-Methylenebisacrylamide (Bisacrylamide) is an orally active acrylamide dimer and crosslinker. N,N'-Methylenebisacrylamide increases CYP2E1, P53, cleaved caspase-3. N,N'-Methylenebisacrylamide promotes hepatic cancer. N,N'-Methylenebisacrylamide changes sperm abnormality rate and sperm count. N,N'-Methylenebisacrylamide decreases the number of various cells in the blood as well as induces liver and testicular damage. N,N'-Methylenebisacrylamide is used to prepare polyacrylamide gel. | ||||||||||||||||||||
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N,N'-Methylenebisacrylamide-d6 | N,N'-Methylenebisacrylamide-d6 is the deuterium labeled N,N'-Methylenebisacrylamide (HY-D0848). N,N'-Methylenebisacrylamide (Bisacrylamide) is an orally active acrylamide dimer and crosslinker. N,N'-Methylenebisacrylamide increases CYP2E1, P53, cleaved caspase-3. N,N'-Methylenebisacrylamide promotes hepatic cancer. N,N'-Methylenebisacrylamide changes sperm abnormality rate and sperm count. N,N'-Methylenebisacrylamide decreases the number of various cells in the blood as well as induces liver and testicular damage. N,N'-Methylenebisacrylamide is used to prepare polyacrylamide gel. | |||||||||||||||||||||
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References
- [1]. Atia MM, et al. Nanocurcumin and curcumin prevent N, N'-methylenebisacrylamide-induced liver damage and promotion of hepatic cancer cell growth. Sci Rep. 2022 May 18;12(1):8319. [Content Brief]
- [2]. George JD, et al. Evaluation of the developmental toxicity of methacrylamide and N,N'-methylenebisacrylamide in Swiss mice. Toxicol Sci. 1998 Nov;46(1):124-33. [Content Brief]
- [3]. de Souza Pereira R. Comparison of biochemical effects produced by calcium ions and by monomers of polyacrylamide (acrylamide and bisacrylamide) on strains of Saccharomyces cerevisiae used for production of chiral synthons. Mol Cell Biochem. 1998 Jan;178(1-2):33-40. [Content Brief]
- [4]. Atia M M, et al. The immunomodulatory role of curcumin and its nanoparticles in mice testis exposed to N, N'-methylenebisacrylamide. Egyptian Academic Journal of Biological Sciences, B. Zoology, 2022, 14(1): 39-54.
- [5]. Atia MM, et al. Rehabilitation of N, N'-methylenebisacrylamide-induced DNA destruction in the testis of adult rats by adipose-derived mesenchymal stem cells and conditional medium. Heliyon. 2024 Nov 14;10(23):e40380. [Content Brief]
- [6]. Sakamoto J, et al. Effects of N,N'-methylene-bis-acrylamide (MBA) on mouse germ cells--sperm count and morphology, and testicular pathology. Arch Toxicol. 1988 Aug;62(1):54-9. [Content Brief]
- [7]. Hashimoto K, et al. Anemia and porphyria caused by N,N'-methylene-bis-acrylamide (MBA) in mice and rats. Arch Toxicol. 1982 May;50(1):47-55. [Content Brief]
