Disuccinimidyl sebacate
Based on 2 publication(s) in Google Scholar
Disuccinimidyl sebacate (DSSeb) is a cross-linker that can be used in the synthesis of the intermolecular cross-linked peptides.
For research use only. We do not sell to patients.
- Purity: 97.0%
- CAS No.: 23024-29-5
- Formula: C18H24N2O8
- Molecular Weight:396.39
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Storage:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
Publications Citing Use of MedChemExpress (MCE) Disuccinimidyl sebacate
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Biological Activity
Chemical Information
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CAS No. 23024-29-5
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Appearance Solid
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Molecular Weight 396.39
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Formula C18H24N2O8
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Color White to off-white
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SMILES
O=C(CCCCCCCCC(ON1C(CCC1=O)=O)=O)ON2C(CCC2=O)=O
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Synonyms
DSSeb; Sebacic acid bis N-succinimidyl ester
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Publications (2)
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Journal Impact Factor
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Most Recent
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Free Radic Biol Med
Nepetin limits NLRP3 inflammasome activation and alleviates NLRP3-driven inflammatory diseases via PINK1-dependent mitophagy. [Abstract]2025 Feb 1:227:420-433. PMID: 39653129 -
J Med Chem
Design, Synthesis, and Bioevaluation of Novel NLRP3 Inhibitor with IBD Immunotherapy from the Virtual Screen. [Abstract]2024 Sep 26;67(18):16612-16634. PMID: 39269610
Solvent & Solubility
DMSO : 50 mg/mL (126.14 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (269 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.5228 mL | 12.6138 mL | 25.2277 mL | 63.0692 mL |
| 5 mM | 0.5046 mL | 2.5228 mL | 5.0455 mL | 12.6138 mL | |
| 10 mM | 0.2523 mL | 1.2614 mL | 2.5228 mL | 6.3069 mL | |
| 15 mM | 0.1682 mL | 0.8409 mL | 1.6818 mL | 4.2046 mL | |
| 20 mM | 0.1261 mL | 0.6307 mL | 1.2614 mL | 3.1535 mL | |
| 25 mM | 0.1009 mL | 0.5046 mL | 1.0091 mL | 2.5228 mL | |
| 30 mM | 0.0841 mL | 0.4205 mL | 0.8409 mL | 2.1023 mL | |
| 40 mM | 0.0631 mL | 0.3153 mL | 0.6307 mL | 1.5767 mL | |
| 50 mM | 0.0505 mL | 0.2523 mL | 0.5046 mL | 1.2614 mL | |
| 60 mM | 0.0420 mL | 0.2102 mL | 0.4205 mL | 1.0512 mL | |
| 80 mM | 0.0315 mL | 0.1577 mL | 0.3153 mL | 0.7884 mL | |
| 100 mM | 0.0252 mL | 0.1261 mL | 0.2523 mL | 0.6307 mL |